PMID- 17102709
OWN - NLM
STAT- MEDLINE
DCOM- 20061211
LR  - 20071115
IS  - 0022-3018 (Print)
IS  - 0022-3018 (Linking)
VI  - 194
IP  - 11
DP  - 2006 Nov
TI  - A comparative meta-analysis of Clinical Global Impressions change in 
      antidepressant trials.
PG  - 845-52
AB  - Two scales of the Clinical Global Impressions (CGI) Scale are frequently used in 
      antidepressant trials. No research has systematically addressed how CGI change 
      compares to change on established measures such as the Hamilton Depression Rating 
      Scale (HAM-D), Montgomery-Asberg Depression Rating Scale, or Beck Depression 
      Inventory. The current meta-analysis examined 75 antidepressant trials in which 
      the CGI was used along with at least one other popular depression measure. The 
      CGI-Severity scale was significantly more conservative than the HAM-D in rating 
      change in double-blind trials, but not in open trials. The Beck Depression 
      Inventory was significantly more conservative than the CGI-Severity. The 
      CGI-Improvement scale was significantly more liberal than the HAM-D or 
      Montgomery-Asberg Depression Rating Scale. Rater bias or scale content may 
      explain differences between measures. Given the often substantial differences 
      between instruments, researchers should use a variety of measures rather than 
      relying on any single tool in assessing treatment response.
FAU - Spielmans, Glen I
AU  - Spielmans GI
AD  - Department of Psychology, State University of New York at Fredonia, Fredonia, New 
      York, USA. Glen.Spielmans@metrostate.edu
FAU - McFall, Joseph P
AU  - McFall JP
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Meta-Analysis
PL  - United States
TA  - J Nerv Ment Dis
JT  - The Journal of nervous and mental disease
JID - 0375402
RN  - 0 (Antidepressive Agents)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Antidepressive Agents/*therapeutic use
MH  - Clinical Trials as Topic/*methods
MH  - Data Interpretation, Statistical
MH  - Depressive Disorder/*diagnosis/*drug therapy/psychology
MH  - Double-Blind Method
MH  - Humans
MH  - Psychiatric Status Rating Scales/*statistics & numerical data
MH  - Psychometrics
MH  - Research Design
MH  - Treatment Outcome
EDAT- 2006/11/15 09:00
MHDA- 2006/12/12 09:00
CRDT- 2006/11/15 09:00
PHST- 2006/11/15 09:00 [pubmed]
PHST- 2006/12/12 09:00 [medline]
PHST- 2006/11/15 09:00 [entrez]
AID - 00005053-200611000-00006 [pii]
AID - 10.1097/01.nmd.0000244554.91259.27 [doi]
PST - ppublish
SO  - J Nerv Ment Dis. 2006 Nov;194(11):845-52. doi: 
      10.1097/01.nmd.0000244554.91259.27.