PMID- 17116422
OWN - NLM
STAT- MEDLINE
DCOM- 20080221
LR  - 20161124
IS  - 1525-2167 (Print)
IS  - 1532-2114 (Linking)
VI  - 8
IP  - 6
DP  - 2007 Dec
TI  - Clinical and echocardiographic determinants of ultrasound lung comets.
PG  - 474-9
AB  - BACKGROUND: Ultrasound lung comets (ULCs) are an echographic sign of 
      extravascular lung water, that originate from water-thickened interlobular septa. 
      AIM: To establish the echocardiographic correlates of ULCs. METHODS: 340 
      in-hospital patients (68 +/- 12years, 115 females) admitted to adult cardiology 
      department underwent upon admission a separate evaluation of chest ULCs and a 
      comprehensive 2D and Doppler echocardiography assessment, including the degree of 
      left ventricular diastolic dysfunction (from 0 = normal to 3 = restrictive 
      pattern). A patient ULC score has been obtained by summing the number of ULCs 
      from each of the scanning spaces in the anterior right and left chest, from 
      second to fifth intercostal space. RESULTS: Multivariate linear regression 
      analysis identified New York Heart Association (NYHA) class (OR = 2.1, CI = 
      1.4-2.9), ejection fraction (OR 0.954, CI = 0.928-0.981) and degree of diastolic 
      dysfunction (OR = 2.438, CI = 1.418-4.190) as the only parameters independently 
      associated to the number of ULCs. CONCLUSION: ULCs are a simple echographic sign 
      of extravascular lung water, more frequently associated with left ventricular 
      diastolic and/or systolic dysfunction. ULCs can usefully integrate the clinical 
      and pathophysiological information provided by conventional 2D and Doppler 
      echocardiography, in patients with known or suspected heart failure and dyspnoea 
      as a presenting symptom.
FAU - Frassi, Francesca
AU  - Frassi F
AD  - Institute of Clinical Physiology, Via Moruzzi 1, Pisa 56010, Italy.
FAU - Gargani, Luna
AU  - Gargani L
FAU - Gligorova, Suzana
AU  - Gligorova S
FAU - Ciampi, Quirino
AU  - Ciampi Q
FAU - Mottola, Gaetano
AU  - Mottola G
FAU - Picano, Eugenio
AU  - Picano E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20061120
PL  - England
TA  - Eur J Echocardiogr
JT  - European journal of echocardiography : the journal of the Working Group on 
      Echocardiography of the European Society of Cardiology
JID - 100890618
SB  - IM
MH  - Aged
MH  - Chi-Square Distribution
MH  - Diagnosis, Differential
MH  - *Echocardiography, Doppler
MH  - Extravascular Lung Water/*diagnostic imaging
MH  - Female
MH  - Humans
MH  - Logistic Models
MH  - Male
EDAT- 2006/11/23 09:00
MHDA- 2008/02/22 09:00
CRDT- 2006/11/23 09:00
PHST- 2006/05/17 00:00 [received]
PHST- 2006/09/15 00:00 [revised]
PHST- 2006/09/30 00:00 [accepted]
PHST- 2006/11/23 09:00 [pubmed]
PHST- 2008/02/22 09:00 [medline]
PHST- 2006/11/23 09:00 [entrez]
AID - S1525-2167(06)00181-8 [pii]
AID - 10.1016/j.euje.2006.09.004 [doi]
PST - ppublish
SO  - Eur J Echocardiogr. 2007 Dec;8(6):474-9. doi: 10.1016/j.euje.2006.09.004. Epub 
      2006 Nov 20.