PMID- 17116487
OWN - NLM
STAT- MEDLINE
DCOM- 20070116
LR  - 20161124
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 171
IP  - 2
DP  - 2006 Dec
TI  - Intravascular large B-cell lymphoma associated with a near-tetraploid karyotype, 
      rearrangement of BCL6, and a t(11;14)(q13;q32).
PG  - 101-4
AB  - Chromosome analysis of a patient with intravascular large B-cell lymphoma (IVL) 
      revealed a complex, near-tetraploid karyotype with 83 chromosomes. Abnormalities 
      included a t(11;14)(q13;q32), which was confirmed with both interphase 
      fluorescence in situ hybridization (FISH) using an IGH/cyclin D1 dual-color, 
      dual-fusion probe set and cyclin D1 immunohistochemical analysis. Abnormality of 
      3q was also evident. Interphase FISH analysis with a dual-color, break-apart 
      probe set confirmed rearrangement of BCL6. To our knowledge, this is the first 
      report of these abnormalities in IVL.
FAU - Rashid, Rumana
AU  - Rashid R
AD  - HMDS Laboratory, Leeds Teaching Hospitals NHS Trust, Great George Street, Leeds, 
      UK. rumana@doctors.org.uk
FAU - Johnson, Roderick J
AU  - Johnson RJ
FAU - Morris, Stephen
AU  - Morris S
FAU - Dickinson, Helen
AU  - Dickinson H
FAU - Czyz, Jarek
AU  - Czyz J
FAU - O'Connor, Sheila J M
AU  - O'Connor SJ
FAU - Owen, Roger G
AU  - Owen RG
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (BCL6 protein, human)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (Proto-Oncogene Proteins c-bcl-6)
SB  - IM
MH  - *Chromosomes, Human, Pair 11
MH  - *Chromosomes, Human, Pair 14
MH  - DNA-Binding Proteins/*genetics
MH  - Female
MH  - Humans
MH  - Karyotyping
MH  - Lymphoma, B-Cell/*genetics/pathology
MH  - Lymphoma, Large B-Cell, Diffuse/*genetics/pathology
MH  - Middle Aged
MH  - *Polyploidy
MH  - Proto-Oncogene Proteins c-bcl-6
MH  - *Translocation, Genetic
MH  - Tumor Cells, Cultured
MH  - Vascular Neoplasms/*genetics/pathology
EDAT- 2006/11/23 09:00
MHDA- 2007/01/17 09:00
CRDT- 2006/11/23 09:00
PHST- 2006/05/05 00:00 [received]
PHST- 2006/06/28 00:00 [revised]
PHST- 2006/07/06 00:00 [accepted]
PHST- 2006/11/23 09:00 [pubmed]
PHST- 2007/01/17 09:00 [medline]
PHST- 2006/11/23 09:00 [entrez]
AID - S0165-4608(06)00451-1 [pii]
AID - 10.1016/j.cancergencyto.2006.07.018 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 2006 Dec;171(2):101-4. doi: 
      10.1016/j.cancergencyto.2006.07.018.