PMID- 17116492
OWN - NLM
STAT- MEDLINE
DCOM- 20070116
LR  - 20131121
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 171
IP  - 2
DP  - 2006 Dec
TI  - Inversion (11)(p15q22) with NUP98-DDX10 fusion gene in pediatric acute myeloid 
      leukemia.
PG  - 122-5
AB  - The inv(11)(p15q22), a rare but recurrent chromosome abnormality that creates a 
      NUP98-DDX10 fusion gene, is associated with de novo or secondary myeloid 
      malignancies. We report a case of acute monocytic leukemia presenting this 
      rearrangement, studied using fluorescence in situ hybridization (FISH) and 
      reverse transcriptase-PCR (RT-PCR). We also review the cases of inv(11) 
      associated with NUP98-DDX10 reported in the literature.
FAU - Morerio, Cristina
AU  - Morerio C
AD  - Dipartimento di Ematologia ed Oncologia Pediatrica, IRCCS Istituto Giannina 
      Gaslini, Largo G Gaslini 5, Genoa, Italy.
FAU - Acquila, Maura
AU  - Acquila M
FAU - Rapella, Annamaria
AU  - Rapella A
FAU - Tassano, Elisa
AU  - Tassano E
FAU - Rosanda, Cristina
AU  - Rosanda C
FAU - Panarello, Claudio
AU  - Panarello C
LA  - eng
SI  - GENBANK/AB040537
SI  - GENBANK/AB040538
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (Nuclear Pore Complex Proteins)
RN  - 0 (Nup98 protein, human)
RN  - EC 3.6.1.- (DDX10 protein, human)
RN  - EC 3.6.4.13 (DEAD-box RNA Helicases)
SB  - IM
MH  - Child
MH  - *Chromosome Inversion
MH  - Chromosomes, Human, Pair 11/*genetics
MH  - DEAD-box RNA Helicases/*genetics
MH  - *Gene Fusion
MH  - Humans
MH  - Leukemia, Myeloid, Acute/drug therapy/enzymology/*genetics
MH  - Male
MH  - Molecular Sequence Data
MH  - Nuclear Pore Complex Proteins/*genetics
RF  - 12
EDAT- 2006/11/23 09:00
MHDA- 2007/01/17 09:00
CRDT- 2006/11/23 09:00
PHST- 2006/05/05 00:00 [received]
PHST- 2006/06/30 00:00 [revised]
PHST- 2006/07/03 00:00 [accepted]
PHST- 2006/11/23 09:00 [pubmed]
PHST- 2007/01/17 09:00 [medline]
PHST- 2006/11/23 09:00 [entrez]
AID - S0165-4608(06)00460-2 [pii]
AID - 10.1016/j.cancergencyto.2006.07.002 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 2006 Dec;171(2):122-5. doi: 
      10.1016/j.cancergencyto.2006.07.002.