PMID- 17120588
OWN - NLM
STAT- MEDLINE
DCOM- 20070116
LR  - 20190715
IS  - 0013-936X (Print)
IS  - 0013-936X (Linking)
VI  - 40
IP  - 20
DP  - 2006 Oct 15
TI  - Biomarkers of PAH exposure in an intertidal fish species from Prince William 
      Sound, Alaska: 2004-2005.
PG  - 6513-7
AB  - Polycyclic aromatic hydrocarbon (PAH) exposure biomarkers were measured in high 
      cockscomb prickleback (Anoplarchus purpurescens) fish collected from both 
      previously oiled and unoiled shore in Prince William Sound (PWS), Alaska, to test 
      the hypothesis that fish living in the nearshore environment of the sound were no 
      longer being exposed to PAH from the Exxon Valdez oil spill. Pricklebacks spend 
      their entire lives in the intertidal zone of rocky shores with short-term 
      movements during feeding and breeding restricted to an area of about 15 meters in 
      diameter. Fish were assayed for the PAH exposure biomarkers, bile fluorescent 
      aromatic compounds (FAC), and liver ethoxyresorufin O-deethylase (EROD) activity 
      (a measure of cytochrome P450 1A (CYP1A) monooxygenase activity). Bile FAC 
      concentrations and EROD activities were low and not significantly different in 
      fish from previously oiled and unoiled sites. The similar low EROD activity and 
      bile FAC concentrations in fish from oiled and unoiled shores, supports the 
      hypothesis that these low-level biomarker responses were not caused by exposure 
      of the fish to residues of the spilled oil.
FAU - Huggett, Robert J
AU  - Huggett RJ
AD  - White Water Associates, Amasa, Michigan 49903, USA. rhuggett@aol.com
FAU - Neff, Jerry M
AU  - Neff JM
FAU - Stegeman, John J
AU  - Stegeman JJ
FAU - Woodin, Bruce
AU  - Woodin B
FAU - Parker, Keith R
AU  - Parker KR
FAU - Brown, John S
AU  - Brown JS
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Environ Sci Technol
JT  - Environmental science & technology
JID - 0213155
RN  - 0 (Biomarkers)
RN  - 0 (Hydrocarbons, Aromatic)
RN  - 0 (Petroleum)
RN  - 0 (Polycyclic Aromatic Hydrocarbons)
RN  - 0 (Water Pollutants, Chemical)
RN  - EC 1.14.14.1 (Cytochrome P-450 CYP1A1)
SB  - IM
CIN - Environ Sci Technol. 2006 Oct 15;40(20):6188-9. PMID: 17120536
MH  - Alaska
MH  - Animals
MH  - Bile/metabolism
MH  - Biomarkers/*analysis
MH  - Cytochrome P-450 CYP1A1/analysis
MH  - Environmental Monitoring/methods
MH  - Fishes/*metabolism
MH  - Hydrocarbons, Aromatic/analysis
MH  - Liver/enzymology
MH  - Oceans and Seas
MH  - Petroleum/analysis
MH  - Polycyclic Aromatic Hydrocarbons/*analysis
MH  - Water Pollutants, Chemical/analysis
EDAT- 2006/11/24 09:00
MHDA- 2007/01/17 09:00
CRDT- 2006/11/24 09:00
PHST- 2006/11/24 09:00 [pubmed]
PHST- 2007/01/17 09:00 [medline]
PHST- 2006/11/24 09:00 [entrez]
AID - 10.1021/es0608489 [doi]
PST - ppublish
SO  - Environ Sci Technol. 2006 Oct 15;40(20):6513-7. doi: 10.1021/es0608489.