PMID- 17123428
OWN - NLM
STAT- MEDLINE
DCOM- 20070123
LR  - 20220316
IS  - 0931-1793 (Print)
IS  - 0931-1793 (Linking)
VI  - 53
IP  - 10
DP  - 2006 Dec
TI  - Porcine acute phase protein concentrations in different diseases in field 
      conditions.
PG  - 488-93
AB  - Five acute phase proteins (APPs) [C-reactive protein (CRP), serum amyloid A 
      (SAA), haptoglobin (Hp), pig-MAP and albumin] were measured in pigs with 
      naturally occurring infections by porcine reproductive and respiratory syndrome 
      virus (PRRSV), Aujeszky's disease virus (ADV), porcine circovirus type 2 (PCV2) 
      and Mycoplasma hyopneumoniae, and in animals with tail and ear bites, arthritis 
      and other acute inflammatory processes. Healthy specific pathogen-free (SPF) pigs 
      were used as controls. In PRRSV-infected pigs, all APPs with the exception of 
      pig-MAP exhibited significant changes compared with controls. In animals affected 
      with ADV only Hp presented changes of statistical significance, whereas pigs with 
      PCV2 showed marked modifications in all APPs tested. Animals affected with 
      Mycoplasmosis showed concentrations of all positive APPs significantly above 
      levels obtained in SPF pigs, though albumin concentrations did not differ from 
      controls. Finally, all APPs studied showed substantial changes in pigs with acute 
      inflammation. The results indicated that an acute phase response was developed in 
      the different diseases studied, this response being higher in animals with 
      clinical signs and concurrent bacterial processes. Haptoglobin would be the APP 
      that better reflects pathological states; however, to get more complete and 
      valuable information it might be advisable to perform APPs profiles including 
      another APP, such as CRP or SAA.
FAU - Parra, M D
AU  - Parra MD
AD  - Animal Medicine and Surgery Department, Faculty of Veterinary Medicine, 
      University of Murcia, 30100 Murcia, Spain.
FAU - Fuentes, P
AU  - Fuentes P
FAU - Tecles, F
AU  - Tecles F
FAU - Martinez-Subiela, S
AU  - Martinez-Subiela S
FAU - Martinez, J S
AU  - Martinez JS
FAU - Munoz, A
AU  - Munoz A
FAU - Ceron, J J
AU  - Ceron JJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - J Vet Med B Infect Dis Vet Public Health
JT  - Journal of veterinary medicine. B, Infectious diseases and veterinary public 
      health
JID - 100955260
RN  - 0 (Acute-Phase Proteins)
RN  - 0 (Haptoglobins)
RN  - 0 (Serum Amyloid A Protein)
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Acute-Phase Proteins/*immunology
MH  - Animals
MH  - Animals, Newborn
MH  - C-Reactive Protein/immunology
MH  - Case-Control Studies
MH  - Circoviridae Infections/blood/immunology/veterinary
MH  - Circovirus/immunology
MH  - Haptoglobins/immunology
MH  - Mycoplasma hyopneumoniae/immunology
MH  - Pneumonia of Swine, Mycoplasmal/blood/immunology
MH  - Porcine Reproductive and Respiratory Syndrome/blood/immunology
MH  - Pseudorabies/blood/immunology
MH  - Serum Amyloid A Protein/immunology
MH  - Specific Pathogen-Free Organisms
MH  - Swine
MH  - Swine Diseases/*blood/*immunology/microbiology/virology
EDAT- 2006/11/25 09:00
MHDA- 2007/01/24 09:00
CRDT- 2006/11/25 09:00
PHST- 2006/11/25 09:00 [pubmed]
PHST- 2007/01/24 09:00 [medline]
PHST- 2006/11/25 09:00 [entrez]
AID - JVB1002 [pii]
AID - 10.1111/j.1439-0450.2006.01002.x [doi]
PST - ppublish
SO  - J Vet Med B Infect Dis Vet Public Health. 2006 Dec;53(10):488-93. doi: 
      10.1111/j.1439-0450.2006.01002.x.