PMID- 17124280
OWN - NLM
STAT- MEDLINE
DCOM- 20070709
LR  - 20220317
IS  - 0931-0509 (Print)
IS  - 0931-0509 (Linking)
VI  - 22
IP  - 2
DP  - 2007 Feb
TI  - The periodontal status of pre-dialysis chronic kidney disease and maintenance 
      dialysis patients.
PG  - 457-64
AB  - BACKGROUND: Periodontitis contributes to generalized inflammation and development 
      of systemic diseases, including atherosclerosis and cardiovascular disease. Its 
      extent in maintenance haemodialysis (HD) patients is disputable and not known in 
      continuous ambulatory peritoneal dialysis (CAPD) and pre-dialysis chronic kidney 
      disease (CKD) patients. METHODS: One hundred and six patients (35 on HD, mean 
      age, 56 years; 33 on CAPD, mean age 51 years; and 38 pre-dialysis CKD stage 2-5, 
      mean age 51 years) from north-eastern Poland were enrolled. Dialysis subjects 
      were recruited from a cohort of 141 HD and 61 CAPD patients. Two control groups 
      comprised 26 generally healthy individuals with advanced periodontitis requiring 
      specialized treatment, and 30 subjects from general population. Gingival index 
      (GI), papillary bleeding index (PBI), plaque index (PI), loss of clinical 
      attachment level (CAL) and community periodontal index of treatment needs (CPITN) 
      were determined according to WHO recommendations. RESULTS: Average values of the 
      indices in HD, CAPD, pre-dialysis CKD, advanced periodontitis and general 
      population subjects were as follows: GI-1.37, 0.95, 1, 2 and 1; PBI-1.45, 0, 0, 
      2.20 and 1; PI-2.05, 1.59, 1, 2 and 1; and CAL loss-5.11, 3.47, 2.50, 4.68 and 
      1.40 mm, respectively. CPITN, analysed separately as community periodontal index 
      and periodontal treatment needs, further indicated a high severity of 
      periodontitis in all renal failure groups as compared with general population 
      subjects. The disease was most advanced in maintenance HD patients-comparable to 
      the full-symptomatic form of periodontitis; then it was successively diminished 
      in CAPD and pre-dialysis CKD subjects. CONCLUSIONS: Periodontal disease is 
      prevalent, severe and under recognized in renal failure patients. Prophylaxis and 
      early dental treatment should be intensified in these subjects, and may be of 
      interdisciplinary importance.
FAU - Borawski, Jacek
AU  - Borawski J
AD  - Department of Nephrology and Transplantology with Dialysis Unit, Medical 
      University, 14 Zurawia Street, 15-540 Bialystok, Poland. jborawski@post.pl
FAU - Wilczynska-Borawska, Magdalena
AU  - Wilczynska-Borawska M
FAU - Stokowska, Wanda
AU  - Stokowska W
FAU - Mysliwiec, Michal
AU  - Mysliwiec M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20061123
PL  - England
TA  - Nephrol Dial Transplant
JT  - Nephrology, dialysis, transplantation : official publication of the European 
      Dialysis and Transplant Association - European Renal Association
JID - 8706402
SB  - IM
CIN - Nephrol Dial Transplant. 2007 Feb;22(2):312-5. PMID: 17071738
CIN - Nephrol Dial Transplant. 2007 Sep;22(9):2722-4. PMID: 17526534
MH  - Adult
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Incidence
MH  - Kidney Failure, Chronic/complications/pathology/*therapy
MH  - Male
MH  - Middle Aged
MH  - *Periodontal Index
MH  - Periodontitis/epidemiology/etiology/*pathology
MH  - Periodontium/*pathology
MH  - Poland/epidemiology
MH  - Prognosis
MH  - *Renal Replacement Therapy
MH  - Retrospective Studies
EDAT- 2006/11/25 09:00
MHDA- 2007/07/10 09:00
CRDT- 2006/11/25 09:00
PHST- 2006/11/25 09:00 [pubmed]
PHST- 2007/07/10 09:00 [medline]
PHST- 2006/11/25 09:00 [entrez]
AID - gfl676 [pii]
AID - 10.1093/ndt/gfl676 [doi]
PST - ppublish
SO  - Nephrol Dial Transplant. 2007 Feb;22(2):457-64. doi: 10.1093/ndt/gfl676. Epub 
      2006 Nov 23.