PMID- 17130026
OWN - NLM
STAT- MEDLINE
DCOM- 20070308
LR  - 20220408
IS  - 0144-3615 (Print)
IS  - 0144-3615 (Linking)
VI  - 26
IP  - 8
DP  - 2006 Nov
TI  - Haematological profile of healthy pregnant women in Ibadan, south-western 
      Nigeria.
PG  - 763-9
AB  - There is a dearth of information on the reference values for haematological 
      indices particularly according to the relevant trimesters of pregnant women in 
      Nigeria. The objective of this study was to provide reference values for Nigerian 
      pregnant women. The study took place at the Adeoyo Maternity Hospital and the 
      University College Hospital, both in Ibadan. This descriptive study was carried 
      out over a period of 8 months. Subjects were apparently healthy pregnant women 
      that satisfied the inclusion and exclusion criteria. The mean values (and 95% 
      confidence intervals, CI) of haematological indices were as follows -- First 
      trimester: Haemoglobin (Hb) 112.44 (101.64 - 123.25) g/l, haematocrit (hct) 35 
      (32 - 38)%, WBC 5.488 (4.025 - 6.950) x 10(9)/l and platelet counts 227.56 
      (165.21 - 289.90) x 10(9)/l;Second trimester: Hb 100.39 (97.85 - 102.92) g/l, hct 
      29.3 (28.5 - 30.1)%, WBC 6.57 (6.19 - 6.95) x 10(9)/l, platelet count 229.56 
      (211.86 - 247.26); and the Third trimester: Hb 98.06 (96.12 - 100.00) g/l, hct 
      29.4 (28.7 - 29.9)%, WBC 6.92 (6.53 - 7.30), platelet count 186.52 (177.67 - 
      195.38) x 10(9)/l. These results were compared with those of 52 non-pregnant age 
      matched women volunteers as controls whose mean haematological indices and 95% CI 
      were: Hb 120.51 (116.61 - 124.41) g/l, hct 36 (25 - 48)%, WBC 5.28 (2.9 - 8.7) x 
      10(9), platelet count 330.87 (176 - 538) x 10(9)/l. The following haematological 
      indices: WBC, platelet counts, RBC, PCT, and PDW, of women between the trimesters 
      showed statistical significance (p value < 0.001 in each case). The WBC is 
      inversely proportional to the PCT and the MCV in the pregnant women was slightly 
      raised. In this study, pregnancy is characterised by lowest values of haemoglobin 
      parameters in trimester three and there are statistically significant differences 
      between the WBC, platelet counts, RBC, PCT, and PDW of women between the three 
      trimesters.
FAU - Akingbola, T S
AU  - Akingbola TS
AD  - Department of Haematology, College of Medicine, University of Ibadan, University 
      College Hospital, Ibadan, Oyo State, Nigeria. tsakingbola@comui.edu.ng
FAU - Adewole, I F
AU  - Adewole IF
FAU - Adesina, O A
AU  - Adesina OA
FAU - Afolabi, K A
AU  - Afolabi KA
FAU - Fehintola, F A
AU  - Fehintola FA
FAU - Bamgboye, E A
AU  - Bamgboye EA
FAU - Aken'ova, Y A
AU  - Aken'ova YA
FAU - Shokunbi, W A
AU  - Shokunbi WA
FAU - Anwo, J A
AU  - Anwo JA
FAU - Nwegbu, M M
AU  - Nwegbu MM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Obstet Gynaecol
JT  - Journal of obstetrics and gynaecology : the journal of the Institute of 
      Obstetrics and Gynaecology
JID - 8309140
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Blood Cell Count
MH  - Female
MH  - *Hematocrit
MH  - Humans
MH  - Nigeria
MH  - Pregnancy/*blood
MH  - Reference Values
EDAT- 2006/11/30 09:00
MHDA- 2007/03/09 09:00
CRDT- 2006/11/30 09:00
PHST- 2006/11/30 09:00 [pubmed]
PHST- 2007/03/09 09:00 [medline]
PHST- 2006/11/30 09:00 [entrez]
AID - T036239837W43261 [pii]
AID - 10.1080/01443610600963770 [doi]
PST - ppublish
SO  - J Obstet Gynaecol. 2006 Nov;26(8):763-9. doi: 10.1080/01443610600963770.