PMID- 17136970 OWN - NLM STAT- MEDLINE DCOM- 20070222 LR - 20220310 IS - 1541-2555 (Print) IS - 1541-2563 (Linking) VI - 2 IP - 1 DP - 2005 Mar TI - Minimally clinically important difference for the UCSD Shortness of Breath Questionnaire, Borg Scale, and Visual Analog Scale. PG - 105-10 AB - Dyspnea is a primary symptom of chronic lung disease and an important outcome measure for clinical trials. Several standardized measures have been developed to evaluate this important symptom and are being used increasingly in clinical trials. The minimally clinically important difference (MCID) is not well defined for these measures but is important in interpreting the clinical meaning of results of studies in this area. The purpose of this paper is to evaluate the MCID for three commonly used measures to assess dyspnea in chronic lung disease: UCSD Shortness of Breath Questionnaire (SOBQ), Borg Scale (Borg), and Visual Analog Scale (VAS). The analysis is based on a retrospective review of published trials evaluating the response to a pulmonary rehabilitation or exercise intervention that is known to produce modest, but clinically meaningful changes for such patients. Using a distribution-based approach based primarily on effect size, the recommended MCID for these measures are: 5-units for the SOBQ, 1-unit for the Borg scale, and approximately 10 to 20 units for the VAS. FAU - Ries, Andrew L AU - Ries AL AD - University of California, UCSD Medical Center 200 W. Arbor Drive, San Diego, California 92103-8377, USA. aries@ucsd.edu LA - eng PT - Journal Article PT - Review PL - England TA - COPD JT - COPD JID - 101211769 SB - IM MH - Data Interpretation, Statistical MH - Dyspnea/*diagnosis MH - Humans MH - Pain Measurement MH - Pulmonary Disease, Chronic Obstructive/*diagnosis MH - *Surveys and Questionnaires RF - 31 EDAT- 2006/12/02 09:00 MHDA- 2007/02/23 09:00 CRDT- 2006/12/02 09:00 PHST- 2006/12/02 09:00 [pubmed] PHST- 2007/02/23 09:00 [medline] PHST- 2006/12/02 09:00 [entrez] AID - 10.1081/copd-200050655 [doi] PST - ppublish SO - COPD. 2005 Mar;2(1):105-10. doi: 10.1081/copd-200050655.