PMID- 17147911 OWN - NLM STAT- MEDLINE DCOM- 20070221 LR - 20161124 IS - 0969-7667 (Print) IS - 0969-7667 (Linking) VI - 13 IP - 3 DP - 2006 Nov TI - Case report: primary infection by human herpesvirus 6 variant a with the onset of myelitis. PG - 72-4 AB - A case of primary infection by human herpesvirus 6 (HHV-6) variant A in a 54-year-old woman, which occurred at the same time as the onset of encephalomyelitis, is reported. The correlation between the two events is discussed. It is speculated that, during the early phase of the infection, the HHV-6 spread to the central nervous system and triggered a pathogenic process that initially developed without symptoms. When the neurological disorders appeared, HHV-6 had already established a latent state: only the virus carried by infected blood cells was detected in the cerebrospinal fluid. FAU - Portolani, Marinella AU - Portolani M AD - Department of Diagnostic Services and Legal Medicine, University of Moderna and Reggio Emilia, Modena, Italy. portolani.marinella@policlinico.mo.it FAU - Pecorari, Monica AU - Pecorari M FAU - Gennari, William AU - Gennari W FAU - Beretti, Francesca AU - Beretti F FAU - Sabbatini, Anna Maria Teresa AU - Sabbatini AM FAU - Casolari, Chiara AU - Casolari C FAU - Rumpianesi, Fabio AU - Rumpianesi F FAU - Cermelli, Claudio AU - Cermelli C FAU - Sintini, Michele AU - Sintini M FAU - Mori, Fernanda AU - Mori F LA - eng PT - Case Reports PT - Journal Article PL - England TA - Herpes JT - Herpes : the journal of the IHMF JID - 9801722 RN - 0 (DNA, Viral) SB - IM MH - Cervical Vertebrae/diagnostic imaging MH - DNA, Viral/blood/cerebrospinal fluid MH - Encephalomyelitis/diagnostic imaging/*virology MH - Female MH - Genetic Variation MH - Herpesvirus 6, Human/*classification/genetics/*isolation & purification MH - Humans MH - Middle Aged MH - Radiography MH - Roseolovirus Infections/*complications/diagnostic imaging/virology EDAT- 2006/12/07 09:00 MHDA- 2007/02/22 09:00 CRDT- 2006/12/07 09:00 PHST- 2006/03/27 00:00 [received] PHST- 2006/08/15 00:00 [accepted] PHST- 2006/12/07 09:00 [pubmed] PHST- 2007/02/22 09:00 [medline] PHST- 2006/12/07 09:00 [entrez] PST - ppublish SO - Herpes. 2006 Nov;13(3):72-4.