PMID- 17153702
OWN - NLM
STAT- MEDLINE
DCOM- 20061221
LR  - 20130502
IS  - 1110-0583 (Print)
IS  - 1110-0583 (Linking)
VI  - 36
IP  - 3
DP  - 2006 Dec
TI  - Effect of the plant Cupressus macro-carpa (Cupressacea) on some haematolo-gical 
      and biochemical parameters of Biomphalaria alexandrina snails.
PG  - 911-24
AB  - The dry powder of the plant aereal part; Cupressus macro-carpa (Cupressacea) was 
      tested against Biomphalaria alexandrina. LC50 & LC90 values were 59.5 & 98.8 ppm, 
      respec-tively. Exposure of B. alexandrina to sublethal concentrations (LC0, LC10 
      & LC25) of C. macrocarpa for three weeks signi-ficantly decreased the number of 
      circulating hemocytes. The magnitude of reduction was increased with increasing 
      of the tested concentration. The main type of cell in the hemolymph of B. 
      alexandrina was the granulocyte (71.8%), followed by large round cells or 
      hyalinocytes (19.0%) and small round cells or undifferentiate cells (9.2%). The 
      percentage of different hemocyte categories was changed in treated snails. In 
      snails maintained at LC25, showed significantly higher percentages of small round 
      cells than controls, 56.2% & 9.2% respectively. Maintainence of B. alexandrina in 
      sublethal concentrations for three weeks significantly reduced protein & 
      hemoglobin content in the hemolymph. Reduction in enzyme activities occurred in 
      the hemolymph and tissues of treated snails. The enzymes were pyruvate kinase 
      (PK), lactat dehydrogenase (LDH), hexokinase (HK) and phosphoenol pyruvate 
      carboxy kinase (PEPCK) which are very important in metabolism of the protein and 
      carbohydrate. The infectivity of Schistosoma mansoni miracidia was greatly 
      reduced by exposure to the sublethal concentrations (LC0, LC10 & LC25) of 
      Cupressus. Infection rate of B. alexandrina reached to 54.5%, 37.5% & 16.7%, 
      respectively compared to control (81.25%). Duration of cercarial shedding and the 
      total periodic cercarial production/snail showed significant reduction while the 
      parasite incubation period was significantly longer (p<0.05).
FAU - El-Sayed, Kamelia A
AU  - El-Sayed KA
AD  - Department of Medical Malacology, Theodor Bilharz Research Institute, P.O. Box 30 
      Imbaba, Giza, Egypt.
LA  - eng
PT  - Journal Article
PL  - Egypt
TA  - J Egypt Soc Parasitol
JT  - Journal of the Egyptian Society of Parasitology
JID - 8102141
RN  - 0 (Molluscacides)
RN  - 0 (Plant Extracts)
SB  - IM
MH  - Animals
MH  - Biomphalaria/*drug effects/enzymology/metabolism/parasitology
MH  - Cupressaceae/*chemistry
MH  - Dose-Response Relationship, Drug
MH  - Hemolymph/*chemistry/*cytology
MH  - Lethal Dose 50
MH  - Molluscacides/*pharmacology
MH  - Pest Control, Biological
MH  - Plant Extracts/*pharmacology
MH  - Schistosoma mansoni/growth & development
MH  - Schistosomiasis mansoni/transmission
EDAT- 2006/12/13 09:00
MHDA- 2006/12/22 09:00
CRDT- 2006/12/13 09:00
PHST- 2006/12/13 09:00 [pubmed]
PHST- 2006/12/22 09:00 [medline]
PHST- 2006/12/13 09:00 [entrez]
PST - ppublish
SO  - J Egypt Soc Parasitol. 2006 Dec;36(3):911-24.