PMID- 17157504 OWN - NLM STAT- MEDLINE DCOM- 20070517 LR - 20160603 IS - 0964-3397 (Print) IS - 0964-3397 (Linking) VI - 23 IP - 2 DP - 2007 Apr TI - Substance use and its implications for the critical care nurses: a literature review. PG - 64-70 AB - BACKGROUND: Illicit drug use in Australia has been increasing and studies indicate that illicit drug users have a higher risk of accidents which may result in the user needing critical care. However, there is a significant gap in the literature specifically pertaining to the implications of drug use in critical care. AIMS: The primary objective was to examine the literature for the physiological effects of methylenedioxymethamphetamine (MDMA), cocaine and amphetamines in critically ill patients. METHODS: A comprehensive literature review was undertaken and a body systems framework was used to categorise the effects of these illicit drugs. RESULTS: The illicit substances addressed have potentially fatal and long-term side effects. For those users involved in accidents or trauma requiring intensive or critical care nursing, the mortality and co-morbidity risks are increased significantly. It is, therefore, important that nurses are able to recognise the specific physiological effects and possible complications that can occur with the use of each illicit drug. CONCLUSION: Both nursing and medical staff need to have a thorough understanding of how illicit substances work and how they can affect the critical care patient and the care they are given. FAU - Brotto, Vanessa AU - Brotto V AD - La Trobe University/Alfred Clinical School of Nursing, Alfred Hospital, Prahran, Melbourne 3004, Australia. vanessa.brotto@deakin.edu.au FAU - Lee, Geraldine AU - Lee G LA - eng PT - Journal Article PT - Review DEP - 20061208 PL - Netherlands TA - Intensive Crit Care Nurs JT - Intensive & critical care nursing JID - 9211274 RN - 0 (Adrenergic Uptake Inhibitors) RN - 0 (Amphetamines) RN - I5Y540LHVR (Cocaine) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) MH - *Adrenergic Uptake Inhibitors/adverse effects/metabolism/pharmacology MH - *Amphetamines/adverse effects/metabolism/pharmacology MH - *Cocaine/adverse effects/metabolism/pharmacology MH - Critical Care/*methods MH - Humans MH - *N-Methyl-3,4-methylenedioxyamphetamine/adverse effects/metabolism/pharmacology MH - Stroke/chemically induced MH - Substance-Related Disorders/*nursing RF - 27 EDAT- 2006/12/13 09:00 MHDA- 2007/05/18 09:00 CRDT- 2006/12/13 09:00 PHST- 2006/07/12 00:00 [received] PHST- 2006/11/01 00:00 [revised] PHST- 2006/11/01 00:00 [accepted] PHST- 2006/12/13 09:00 [pubmed] PHST- 2007/05/18 09:00 [medline] PHST- 2006/12/13 09:00 [entrez] AID - S0964-3397(06)00135-2 [pii] AID - 10.1016/j.iccn.2006.11.001 [doi] PST - ppublish SO - Intensive Crit Care Nurs. 2007 Apr;23(2):64-70. doi: 10.1016/j.iccn.2006.11.001. Epub 2006 Dec 8.