PMID- 17160949
OWN - NLM
STAT- MEDLINE
DCOM- 20080204
LR  - 20061212
IS  - 1003-9406 (Print)
IS  - 1003-9406 (Linking)
VI  - 23
IP  - 6
DP  - 2006 Dec
TI  - [ZNF217 gene was detected in ovarian serous cystadenocarcinoma by fluorescence in 
      situ hybridization].
PG  - 665-7
AB  - OBJECTIVE: To investigate amplification of zinc finger protein 217 (ZNF217) gene 
      in ovarian serous cystadenocarcinoma and its clinical significance. METHODS: 
      Twenty three specimens of ovarian carcinoma, 10 specimens of ovarian benign 
      tumors and 7 specimens of normal ovaries and two ovarian cancer cell lines, SKOV3 
      and HO-8910 were examined by fluorescence in situ hybridization (FISH). RESULTS: 
      The amplification of ZNF217 was gained in 12 case of ovarian cancers, there was 
      only 1 case in ovarian benign tumor and not amplication in normal ovary. 
      CONCLUSION: The amplification of ZNF217 is associated with ovarian cancer. 
      Oncogenes ZNF217 maybe play a role in cell differentiation and indicate poorer 
      survival in patients with ovarian cancer.
FAU - Zhong, Mei
AU  - Zhong M
AD  - Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical 
      University, Guangzhou, Guangdong, 510515, P. R. China. zhongmei@fimmu.com
FAU - Li, Jing
AU  - Li J
FAU - Ding, Yan-qing
AU  - Ding YQ
FAU - Song, Lan-lin
AU  - Song LL
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi
JT  - Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese 
      journal of medical genetics
JID - 9425197
RN  - 0 (Trans-Activators)
RN  - 0 (ZNF217 protein, human)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cell Differentiation
MH  - Cell Line, Tumor
MH  - Cystadenocarcinoma, Serous/*genetics/pathology
MH  - Cystadenoma, Serous/genetics/pathology
MH  - Female
MH  - Gene Amplification
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Ovarian Neoplasms/*genetics/pathology
MH  - Survival Analysis
MH  - Trans-Activators/*genetics
EDAT- 2006/12/13 09:00
MHDA- 2008/02/05 09:00
CRDT- 2006/12/13 09:00
PHST- 2006/12/13 09:00 [pubmed]
PHST- 2008/02/05 09:00 [medline]
PHST- 2006/12/13 09:00 [entrez]
AID - 940623159 [pii]
PST - ppublish
SO  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2006 Dec;23(6):665-7.