PMID- 17161980
OWN - NLM
STAT- MEDLINE
DCOM- 20070724
LR  - 20070430
IS  - 1570-0232 (Print)
IS  - 1570-0232 (Linking)
VI  - 850
IP  - 1-2
DP  - 2007 May 1
TI  - The study on the chromatographic fingerprint of Fructus xanthii by microwave 
      assisted extraction coupled with GC-MS.
PG  - 241-8
AB  - The chromatographic fingerprint of Fructus xanthii, a kind of Traditional Chinese 
      Medicines (TCMs), was studied by microwave assisted extraction (MAE) coupled with 
      gas chromatography-mass spectrometry (GC-MS). The optimized conditions of MAE 
      were examined. The method of MAE was evaluated in contrast to heat reflux 
      extraction (HRE) method and by the validation tests of precision and 
      repeatability. The relative standard deviations (RSDs) of retention time and peak 
      area of each component were less than 0.2% and 6%, respectively. Twenty-five 
      different batches of samples collected from different producing areas and the 
      toasting process of F. xanthii were studied. The characteristic differences in 
      the producing areas and the chemical variances in the toasting process were 
      obtained and studied by principal components analysis (PCA) and similarity 
      analysis. The trends of main varying components were attempted to be described in 
      order to specify the related pharmacology and toxicology in crude and toasted 
      samples. The results suggest that the chromatographic fingerprint developed by 
      MAE coupled with GC-MS provides useful information to reveal the quality of F. 
      xanthii and evaluate the quality changes in the producing process.
FAU - Ruan, Gui-Hua
AU  - Ruan GH
AD  - School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 
      510275, P.R. China.
FAU - Li, Gong-Ke
AU  - Li GK
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20061211
PL  - Netherlands
TA  - J Chromatogr B Analyt Technol Biomed Life Sci
JT  - Journal of chromatography. B, Analytical technologies in the biomedical and life 
      sciences
JID - 101139554
SB  - IM
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - *Microwaves
MH  - Xanthium/*chemistry
EDAT- 2006/12/13 09:00
MHDA- 2007/07/25 09:00
CRDT- 2006/12/13 09:00
PHST- 2006/08/02 00:00 [received]
PHST- 2006/11/09 00:00 [revised]
PHST- 2006/11/21 00:00 [accepted]
PHST- 2006/12/13 09:00 [pubmed]
PHST- 2007/07/25 09:00 [medline]
PHST- 2006/12/13 09:00 [entrez]
AID - S1570-0232(06)00993-7 [pii]
AID - 10.1016/j.jchromb.2006.11.036 [doi]
PST - ppublish
SO  - J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 1;850(1-2):241-8. doi: 
      10.1016/j.jchromb.2006.11.036. Epub 2006 Dec 11.