PMID- 17167900
OWN - NLM
STAT- MEDLINE
DCOM- 20070110
LR  - 20220310
IS  - 0079-6123 (Print)
IS  - 0079-6123 (Linking)
VI  - 157
DP  - 2006
TI  - Receptor tyrosine kinase B-mediated excitatory synaptogenesis.
PG  - 15-24
AB  - The receptor tyrosine kinase B, TrkB, is the high-affinity receptor for 
      brain-derived neurotrophic factor (BDNF). Much evidence supports a role for TrkB 
      signaling in excitatory synapse formation. There have been a number of recent 
      advances in understanding the cell biology of TrkB-mediated excitatory 
      synaptogenesis. The predominant mechanism by which TrkB supports excitatory 
      synaptogenesis appears to be due to cell-autonomous signaling in both pre- and 
      postsynaptic cells. This signaling appears to contribute to the growth and 
      stabilization processes necessary for the net formation of synapses during 
      development. Further, the molecular mechanisms by which TrkB contributes to these 
      growth and stabilization processes are beginning to be elucidated.
FAU - Luikart, Bryan W
AU  - Luikart BW
AD  - Center for Developmental Biology, and Kent Waldrep Foundation Center for Basic 
      Neuroscience Research on Nerve Growth and Regeneration, University of Texas 
      Southwestern Medical Center, Dallas, TX 75390, USA. bluikart@yahoo.com
FAU - Parada, Luis F
AU  - Parada LF
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Netherlands
TA  - Prog Brain Res
JT  - Progress in brain research
JID - 0376441
RN  - 0 (Excitatory Amino Acids)
RN  - EC 2.7.10.1 (Receptor, trkB)
SB  - IM
MH  - Animals
MH  - Excitatory Amino Acids/physiology
MH  - Humans
MH  - Receptor, trkB/*physiology
MH  - Synapses/*physiology
RF  - 90
EDAT- 2006/12/16 09:00
MHDA- 2007/01/11 09:00
CRDT- 2006/12/16 09:00
PHST- 2006/12/16 09:00 [pubmed]
PHST- 2007/01/11 09:00 [medline]
PHST- 2006/12/16 09:00 [entrez]
AID - S0079-6123(06)57002-5 [pii]
AID - 10.1016/s0079-6123(06)57002-5 [doi]
PST - ppublish
SO  - Prog Brain Res. 2006;157:15-24. doi: 10.1016/s0079-6123(06)57002-5.