PMID- 17171585
OWN - NLM
STAT- MEDLINE
DCOM- 20070223
LR  - 20151119
IS  - 0935-8943 (Print)
IS  - 0935-8943 (Linking)
VI  - 85
IP  - 12
DP  - 2006 Dec
TI  - [Diagnosis and treatment of laryngopharyngeal reflux].
PG  - 919-24; quiz 925-6
AB  - BACKGROUND: During the last decades an increased prevalence of reflux disease can 
      be observed. Otolaryngologists play an increasing role in the treatment of 
      patients suffering from laryngopharyngeal reflux (LPR). Typical symptoms for LPR 
      are globus sensation, dysphagia, throat clearing, chronic cough and hoarseness. 
      The most frequent laryngoscopic finding in patients suffering from LPR is a 
      posterior commissure hypertrophy. LPR is confirmed by laryngoscopy, LPR-related 
      laryngoscopy scoring, 24-hour dual-probe pH-monitoring, and by empiric trial with 
      proton pump inhibitors (PPI). For therapy PPI-medication in a dosage of 40 mg BID 
      for at least 3 months is successful in many patients. Additional lifestyle 
      modifications can also have a positive effect. When medical management fails, 
      further diagnostic procedures should be initiated. CONCLUSION: In patients 
      suffering from unspecific laryngeal and respiratory symptoms LPR is an important 
      differential diagnosis.
FAU - Reichel, O
AU  - Reichel O
AD  - Klinik fur Hals-Nasen-Ohrenheilkunde, Ludwig-Maximilians-Universitat, Munchen. 
      Oliver.Reichel@med.uni-muenchen.de
FAU - Hagedorn, H
AU  - Hagedorn H
FAU - Berghaus, A
AU  - Berghaus A
LA  - ger
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Diagnostik und Therapie des laryngopharyngealen Reflux.
PL  - Germany
TA  - Laryngorhinootologie
JT  - Laryngo- rhino- otologie
JID - 8912371
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Adult
MH  - Chronic Disease
MH  - Cough/etiology
MH  - Deglutition Disorders/etiology
MH  - Diagnosis, Differential
MH  - Esophageal pH Monitoring
MH  - Female
MH  - Fundoplication
MH  - Gastroesophageal Reflux/diagnosis
MH  - Hoarseness/etiology
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - *Hypopharynx
MH  - Laryngeal Diseases/diagnosis
MH  - Laryngoscopy
MH  - Life Style
MH  - Male
MH  - Middle Aged
MH  - *Pharyngeal Diseases/diagnosis/therapy
MH  - Proton Pump Inhibitors
MH  - Surveys and Questionnaires
MH  - Time Factors
RF  - 19
EDAT- 2006/12/16 09:00
MHDA- 2007/02/24 09:00
CRDT- 2006/12/16 09:00
PHST- 2006/12/16 09:00 [pubmed]
PHST- 2007/02/24 09:00 [medline]
PHST- 2006/12/16 09:00 [entrez]
AID - 10.1055/s-2006-925445 [doi]
PST - ppublish
SO  - Laryngorhinootologie. 2006 Dec;85(12):919-24; quiz 925-6. doi: 
      10.1055/s-2006-925445.