PMID- 17175125 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20071005 LR - 20070813 IS - 1872-6283 (Electronic) IS - 0379-0738 (Linking) VI - 171 IP - 2-3 DP - 2007 Sep 13 TI - Factors influencing the contamination of UK banknotes with drugs of abuse. PG - 165-70 AB - Bank of England banknotes sampled from different locations in the UK have been analysed for the presence of cocaine, diamorphine (DAM), Delta(9)-tetrahydrocannabinol (THC) and 3,4-methylenedioxymethamphetamine (MDMA). A database of the contamination detected is routinely used as a benchmark against which the contamination detected on seized banknotes can be compared. Evidence presented at court details how banknotes seized from a suspect may differ from banknotes in general circulation in terms of their contamination with controlled drugs. A question arising from such evidence is whether seized banknotes could have become contaminated through being in circulation in drug "hot spots". In order to address this issue, a Plackett-Burman experimental design was used to investigate the influence of source location and other factors on banknote contamination with drugs of abuse. Banknotes were drawn from banks in eight regions throughout the UK. Each location could be described by a unique combination of the factors under investigation, namely whether the location was rural or urban, in the North or South of the UK, and whether it was a port of entry. The socio-economic class and the proportion of drug offenders in the area and the denomination of the banknotes were also considered as potentially influential factors. Indices were calculated to describe the degree to which samples were contaminated with different drugs, and normal probability plots were used to identify the factors that could account for the contamination observed. Whilst some factors were more influential than others, it was shown that, at the 95% confidence level, none of the proposed factors were significant influences on the contamination. Cocaine contamination on banknotes has been shown to follow a log-normal distribution. It was, therefore, possible to calculate F- and t-statistics to compare the cocaine contamination on the entire sample set with that detected on a second sample set consisting of banknotes all drawn from a single bank branch. It was shown that both inter-bank samples and intra-bank samples had similar variance and similar contamination levels at the 95% confidence level. This suggests that there are no significant regional trends in the contamination of banknotes with drugs of abuse across the UK. FAU - Ebejer, Karl A AU - Ebejer KA AD - Mass Spec Analytical Ltd., Filton, Bristol BS99 7AR, UK. FAU - Lloyd, Gavin R AU - Lloyd GR FAU - Brereton, Richard G AU - Brereton RG FAU - Carter, James F AU - Carter JF FAU - Sleeman, Richard AU - Sleeman R LA - eng PT - Journal Article DEP - 20061218 PL - Ireland TA - Forensic Sci Int JT - Forensic science international JID - 7902034 EDAT- 2006/12/19 09:00 MHDA- 2006/12/19 09:01 CRDT- 2006/12/19 09:00 PHST- 2006/08/11 00:00 [received] PHST- 2006/10/24 00:00 [revised] PHST- 2006/11/07 00:00 [accepted] PHST- 2006/12/19 09:00 [pubmed] PHST- 2006/12/19 09:01 [medline] PHST- 2006/12/19 09:00 [entrez] AID - S0379-0738(06)00672-4 [pii] AID - 10.1016/j.forsciint.2006.11.004 [doi] PST - ppublish SO - Forensic Sci Int. 2007 Sep 13;171(2-3):165-70. doi: 10.1016/j.forsciint.2006.11.004. Epub 2006 Dec 18.