PMID- 17180205
OWN - NLM
STAT- MEDLINE
DCOM- 20070212
LR  - 20111117
IS  - 1473-0197 (Print)
IS  - 1473-0189 (Linking)
VI  - 7
IP  - 1
DP  - 2007 Jan
TI  - Integrated thin-film polymer/fullerene photodetectors for on-chip microfluidic 
      chemiluminescence detection.
PG  - 58-63
AB  - We report the use of solution-processed thin-film organic photodiodes for 
      microscale chemiluminescence. The active layer of the photodiodes comprised a 1 : 
      1 blend by weight of the conjugated polymer poly(3-hexylthiophene) [P3HT] and 
      [6,6]-phenyl-C(61)-butyric acid-methylester [PCBM]--a soluble derivative of 
      C(60). The devices had an active area of 1 mm x 1 mm, and a broad-band response 
      from 350 to 700 nm, with an external quantum efficiency of more than 50% between 
      450 and 550 nm. The photodiodes have a simple layered structure that permits 
      facile integration with planar chip-based systems. To evaluate the suitability of 
      the organic devices as integrated detectors for microscale chemiluminescence, a 
      peroxyoxalate based chemiluminescence reaction (PO-CL) was monitored within a 
      poly(dimethyl-siloxane) (PDMS) microfluidic device. Quantitation of hydrogen 
      peroxide indicated excellent linearity and yielded a detection limit of 10 
      microM, comparable with previously reported results using micromachined silicon 
      microfluidic chips with integrated silicon photodiodes. The combination of 
      organic photodiodes with PDMS microfluidic chips offers a means of creating 
      compact, sensitive and potentially low-cost microscale CL devices with 
      wide-ranging applications in chemical and biological analysis and clinical 
      diagnostics.
FAU - Wang, Xuhua
AU  - Wang X
AD  - Experimental Solid State Physics Group, Blackett Laboratory, Imperial College 
      London, UK.
FAU - Hofmann, Oliver
AU  - Hofmann O
FAU - Das, Rupa
AU  - Das R
FAU - Barrett, Edward M
AU  - Barrett EM
FAU - deMello, Andrew J
AU  - deMello AJ
FAU - deMello, John C
AU  - deMello JC
FAU - Bradley, Donal D C
AU  - Bradley DD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20061017
PL  - England
TA  - Lab Chip
JT  - Lab on a chip
JID - 101128948
RN  - 0 (Dimethylpolysiloxanes)
RN  - 0 (Fullerenes)
RN  - 0 (Silicones)
RN  - 0 (Thiophenes)
RN  - 0 (poly(3-hexylthiophene))
RN  - 63148-62-9 (baysilon)
SB  - IM
MH  - Dimethylpolysiloxanes/*chemistry
MH  - Equipment Design
MH  - Fullerenes/*chemistry
MH  - *Luminescent Measurements/instrumentation/methods
MH  - *Microfluidic Analytical Techniques/instrumentation/methods
MH  - Photochemistry
MH  - Sensitivity and Specificity
MH  - Silicones/*chemistry
MH  - Thiophenes/*chemistry
EDAT- 2006/12/21 09:00
MHDA- 2007/02/13 09:00
CRDT- 2006/12/21 09:00
PHST- 2006/12/21 09:00 [pubmed]
PHST- 2007/02/13 09:00 [medline]
PHST- 2006/12/21 09:00 [entrez]
AID - 10.1039/b611067c [doi]
PST - ppublish
SO  - Lab Chip. 2007 Jan;7(1):58-63. doi: 10.1039/b611067c. Epub 2006 Oct 17.