PMID- 17181106
OWN - NLM
STAT- MEDLINE
DCOM- 20070213
LR  - 20191110
IS  - 1050-6586 (Print)
IS  - 1050-6586 (Linking)
VI  - 20
IP  - 6
DP  - 2006 Nov-Dec
TI  - The relationship between atopy and chronic rhinosinusitis.
PG  - 625-8
AB  - BACKGROUND: The aim of this study was to determine whether atopy influences 
      either clinical and radiological severity or surgical revision rates in patients 
      with chronic rhinosinusitis (CRS). METHODS: Patients who had been scheduled for 
      endoscopic sinus surgery were classified as having CRS or nasal polyposis. Their 
      atopic status was determined by ImmunoCAP testing. Disease severity was assessed 
      clinically by the Lund symptom and Sino-Nasal Outcome Test 20 (SNOT-20) 
      quality-of-life scores and radiologically by the Lund-Mackay CT score. RESULTS: 
      One hundred ninety-three consecutive patients with rhinosinusitis were included 
      in the study. The prevalence of atopy in this group was found to be 30%. No 
      association was found between atopic status and Lund symptom scores. Analysis of 
      the SNOT-20 scores indicated that atopic patients had higher sneezing scores (p < 
      0.03), reduced productivity (p < 0.01), and reduced concentration (p < 0.01). The 
      mean CT score was significantly higher in the atopic patients than in nonatopic 
      patients overall (14.2+/-1.6 versus 12.2+/-1.3; p = 0.05), although within each 
      of the clinical subgroups no statistically significant relationship was observed 
      between a patients' atopic status and their CT scores. The rate of revision 
      surgery was not significantly different between atopic and nonatopic patients. 
      CONCLUSION: These results suggest that atopic status has minimal impact on the 
      severity of CRS.
FAU - Robinson, Simon
AU  - Robinson S
AD  - Wakefield Hospital, Wellington, New Zealand.
FAU - Douglas, Richard
AU  - Douglas R
FAU - Wormald, Peter-John
AU  - Wormald PJ
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Rhinol
JT  - American journal of rhinology
JID - 8807268
RN  - 0 (Antibodies, Anti-Idiotypic)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Antibodies, Anti-Idiotypic/analysis
MH  - Chronic Disease
MH  - Endoscopy
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Hypersensitivity/*complications/epidemiology/immunology
MH  - Immunoglobulin E/immunology
MH  - Male
MH  - Middle Aged
MH  - Otorhinolaryngologic Surgical Procedures/methods
MH  - Prevalence
MH  - Prognosis
MH  - Retrospective Studies
MH  - Rhinitis/*diagnosis/etiology/surgery
MH  - Severity of Illness Index
MH  - Sinusitis/*diagnosis/etiology/surgery
EDAT- 2006/12/22 09:00
MHDA- 2007/02/14 09:00
CRDT- 2006/12/22 09:00
PHST- 2006/12/22 09:00 [pubmed]
PHST- 2007/02/14 09:00 [medline]
PHST- 2006/12/22 09:00 [entrez]
AID - 10.2500/ajr.2006.20.2907 [doi]
PST - ppublish
SO  - Am J Rhinol. 2006 Nov-Dec;20(6):625-8. doi: 10.2500/ajr.2006.20.2907.