PMID- 17194488 OWN - NLM STAT- MEDLINE DCOM- 20070405 LR - 20191210 IS - 0166-4328 (Print) IS - 0166-4328 (Linking) VI - 177 IP - 2 DP - 2007 Feb 27 TI - Inhibition of lesion-induced neurogenesis impaired behavioral recovery in adult ring doves. PG - 358-63 AB - We have previously shown that electrolytic lesion-induced neurogenesis in the ventromedial nucleus of the hypothalamus (VMN) is significantly correlated with the recovery of courtship behavior in adult male ring doves. Here we revealed that reduction of lesion-induced neurogenesis in VMN impaired the behavioral recovery suggesting therefore a causal link between neurogenesis and behavioral recovery. Our results lend support that adult neurogenesis is latent in repair of injured brain. FAU - Chen, Gang AU - Chen G AD - Department of Psychology, Rutgers University, Newark, NJ 07102, United States. chenga@ohsu.edu FAU - Cheng, Mei-Fang AU - Cheng MF LA - eng GR - NS-36924/NS/NINDS NIH HHS/United States GR - R01 HD047761-01A2/HD/NICHD NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't DEP - 20061227 PL - Netherlands TA - Behav Brain Res JT - Behavioural brain research JID - 8004872 RN - 0 (Amino Acids) RN - 0 (Glial Fibrillary Acidic Protein) RN - 0 (dolaisoleucine) RN - EC 4.2.1.11 (Phosphopyruvate Hydratase) SB - IM MH - Amino Acids MH - Animals MH - Cell Count/methods MH - Columbidae MH - Glial Fibrillary Acidic Protein/metabolism MH - Immunohistochemistry MH - *Inhibition, Psychological MH - Male MH - Neurons/*physiology MH - Phosphopyruvate Hydratase/metabolism MH - Recovery of Function/*physiology MH - Sexual Behavior, Animal MH - Ventromedial Hypothalamic Nucleus/injuries/*pathology EDAT- 2006/12/30 09:00 MHDA- 2007/04/06 09:00 CRDT- 2006/12/30 09:00 PHST- 2006/08/15 00:00 [received] PHST- 2006/11/20 00:00 [revised] PHST- 2006/11/21 00:00 [accepted] PHST- 2006/12/30 09:00 [pubmed] PHST- 2007/04/06 09:00 [medline] PHST- 2006/12/30 09:00 [entrez] AID - S0166-4328(06)00649-8 [pii] AID - 10.1016/j.bbr.2006.11.041 [doi] PST - ppublish SO - Behav Brain Res. 2007 Feb 27;177(2):358-63. doi: 10.1016/j.bbr.2006.11.041. Epub 2006 Dec 27.