PMID- 17195188
OWN - NLM
STAT- MEDLINE
DCOM- 20070402
LR  - 20071203
IS  - 1058-8388 (Print)
IS  - 1058-8388 (Linking)
VI  - 236
IP  - 2
DP  - 2007 Feb
TI  - Comparison of the expression patterns of newly identified zebrafish retinoic acid 
      and retinoid X receptors.
PG  - 587-95
AB  - Retinoic acid (RA) signaling is important for multiple aspects of embryonic 
      development and tissue homeostasis. Heterodimers of retinoic acid receptors 
      (RARs) and retinoid X receptors (RXRs) transduce RA signaling. It is not yet 
      clear how the diversity of receptor combinations relates to the diversity of 
      functions for RA. The expression patterns of three zebrafish RARs and four RXRs 
      were reported recently. Here, we identify an additional RAR, a zebrafish RARgamma 
      paralog, and two additional RXRs, duplicates of the previously identified 
      RXRalpha and RXRgamma. Thus, the zebrafish genome contains duplicates of each RAR 
      and RXR gene. All zebrafish RAR and RXR paralogs have overlapping and distinct 
      areas of expression, as might be expected for duplicate genes in the process of 
      diverging in function. By representing what is potentially the complete set of 
      zebrafish RARs and RXRs, this study provides a valuable reference for future 
      functional studies of the individual zebrafish RARs and RXRs.
FAU - Waxman, Joshua S
AU  - Waxman JS
AD  - Developmental Genetics Program and Department of Cell Biology, Skirball Institute 
      of Biomolecular Medicine, New York University School of Medicine, New York, New 
      York 10016, USA.
FAU - Yelon, Deborah
AU  - Yelon D
LA  - eng
SI  - GENBANK/AAA50049
SI  - GENBANK/AAA50050
SI  - GENBANK/AAC15588
SI  - GENBANK/AAC15589
SI  - GENBANK/AAC32789
SI  - GENBANK/AAC80008
SI  - GENBANK/AAD16119
SI  - GENBANK/AAD23398
SI  - GENBANK/AAD45325
SI  - GENBANK/AAF80975
SI  - GENBANK/AAH10216
SI  - GENBANK/AAH72132
SI  - GENBANK/AAH99776
SI  - GENBANK/AAL02360
SI  - GENBANK/AAL02361
SI  - GENBANK/AAL02362
SI  - GENBANK/AAL14642
SI  - GENBANK/AAM46149
SI  - GENBANK/AAP33792
SI  - GENBANK/AAU12572
SI  - GENBANK/AAW34268
SI  - GENBANK/BAB83838
SI  - GENBANK/CAA35602
SI  - GENBANK/CAA35603
SI  - GENBANK/CAA49562
SI  - GENBANK/CAA49565
SI  - GENBANK/CAA71177
SI  - GENBANK/CAB43870
SI  - GENBANK/CAD45002
SI  - GENBANK/CAD57002
SI  - GENBANK/EF028131
SI  - GENBANK/EF028132
SI  - GENBANK/EF028133
SI  - RefSeq/NP_000955
SI  - RefSeq/NP_000956
SI  - RefSeq/NP_000957
SI  - RefSeq/NP_001012663
SI  - RefSeq/NP_001027925
SI  - RefSeq/NP_002948
SI  - RefSeq/NP_005027
SI  - RefSeq/NP_008848
SI  - RefSeq/NP_033133
SI  - RefSeq/NP_035373
SI  - RefSeq/NP_035374
SI  - RefSeq/NP_035435
SI  - RefSeq/NP_035436
SI  - RefSeq/NP_036937
SI  - RefSeq/NP_068811
SI  - RefSeq/NP_113716
SI  - RefSeq/NP_113953
SI  - RefSeq/NP_507103
SI  - RefSeq/NP_571228
SI  - RefSeq/NP_571292
SI  - RefSeq/NP_571313
SI  - RefSeq/NP_571350
SI  - RefSeq/NP_571414
SI  - RefSeq/NP_989867
SI  - RefSeq/NP_990625
SI  - RefSeq/NP_990657
SI  - RefSeq/XP_536146
SI  - RefSeq/XP_538856
SI  - RefSeq/XP_548399
SI  - SWISSPROT/P28699
SI  - SWISSPROT/P51126
SI  - SWISSPROT/P51129
GR  - F32 HL083591-01/HL/NHLBI NIH HHS/United States
GR  - R01 HL069594/HL/NHLBI NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - Dev Dyn
JT  - Developmental dynamics : an official publication of the American Association of 
      Anatomists
JID - 9201927
RN  - 0 (Receptors, Retinoic Acid)
RN  - 0 (Retinoid X Receptors)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Cloning, Molecular
MH  - Cluster Analysis
MH  - *Gene Expression Profiling
MH  - In Situ Hybridization
MH  - Molecular Sequence Data
MH  - *Phylogeny
MH  - Receptors, Retinoic Acid/genetics/*metabolism
MH  - Retinoid X Receptors/genetics/*metabolism
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Sequence Analysis, DNA
MH  - Zebrafish/*embryology/*genetics/metabolism
EDAT- 2006/12/30 09:00
MHDA- 2007/04/03 09:00
CRDT- 2006/12/30 09:00
PHST- 2006/12/30 09:00 [pubmed]
PHST- 2007/04/03 09:00 [medline]
PHST- 2006/12/30 09:00 [entrez]
AID - 10.1002/dvdy.21049 [doi]
PST - ppublish
SO  - Dev Dyn. 2007 Feb;236(2):587-95. doi: 10.1002/dvdy.21049.