PMID- 17201620
OWN - NLM
STAT- MEDLINE
DCOM- 20070301
LR  - 20070104
IS  - 1044-5463 (Print)
IS  - 1044-5463 (Linking)
VI  - 16
IP  - 6
DP  - 2006 Dec
TI  - Substance use, suicidality, and adolescent-onset schizophrenia: an Israeli 
      10-year retrospective study.
PG  - 767-75
AB  - OBJECTIVE: The aim of this study was to investigate the link between the use of 
      specific types of substances and suicidality in adolescent inpatients with 
      schizophrenia and schizoaffective disorder. METHODS: We performed a 10-year 
      naturalistic retrospective study of 178 adolescent inpatients diagnosed as 
      suffering from either schizophrenia or schizoaffective disorder. A comparison was 
      made between the suicide-attempting adolescent inpatients and the non-attempting 
      subjects, by the use of specific types of substances, measurements of psychotic, 
      depressive, and aggressive symptoms, and clinical data reported during their 
      hospitalization. RESULTS: The suicide attempters reported considerably greater 
      usage of inhalants and lysergic acid diethylamide (LSD). Alcohol and 
      methylene-dioxy-methylamphetamine (MDMA) were also used significantly more by 
      this group. However, no differences were found in the usage of cannabis, 
      amphetamines, cocaine, and opiates. The suicide-attempting patients were found to 
      have had more previous psychiatric admissions, a greater level of deliberate 
      self-harm behavior, and a higher level of suicide ideation, but a decreased 
      severity of psychotic symptoms. CONCLUSIONS: This study is the first report of 
      the association between specific types of substances and suicidality in the 
      high-risk population of adolescent psychotic inpatients. The strong association 
      between inhalants, LSD, alcohol, and MDMA with suicidality is relevant to suicide 
      prevention and intervention programs in adolescent-onset schizophrenia.
FAU - Shoval, Gal
AU  - Shoval G
AD  - Adolescent Inpatient Unit, Geha Mental Health Center, Petah Tiqva, Israel. 
      shovgal@post.tau.ac.il
FAU - Sever, Jonathan
AU  - Sever J
FAU - Sher, Leo
AU  - Sher L
FAU - Diller, Robyne
AU  - Diller R
FAU - Apter, Alan
AU  - Apter A
FAU - Weizman, Abraham
AU  - Weizman A
FAU - Zalsman, Gil
AU  - Zalsman G
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Child Adolesc Psychopharmacol
JT  - Journal of child and adolescent psychopharmacology
JID - 9105358
SB  - IM
MH  - Adolescent
MH  - Age of Onset
MH  - Aggression/psychology
MH  - Female
MH  - Hospitalization
MH  - Humans
MH  - Israel
MH  - Male
MH  - Psychiatric Status Rating Scales
MH  - Psychotic Disorders/psychology
MH  - Retrospective Studies
MH  - *Schizophrenic Psychology
MH  - Self-Injurious Behavior
MH  - Substance-Related Disorders/*psychology
MH  - Suicide, Attempted/*psychology
EDAT- 2007/01/05 09:00
MHDA- 2007/03/03 09:00
CRDT- 2007/01/05 09:00
PHST- 2007/01/05 09:00 [pubmed]
PHST- 2007/03/03 09:00 [medline]
PHST- 2007/01/05 09:00 [entrez]
AID - 10.1089/cap.2006.16.767 [doi]
PST - ppublish
SO  - J Child Adolesc Psychopharmacol. 2006 Dec;16(6):767-75. doi: 
      10.1089/cap.2006.16.767.