PMID- 17201713
OWN - NLM
STAT- MEDLINE
DCOM- 20070124
LR  - 20070104
IS  - 0013-9580 (Print)
IS  - 0013-9580 (Linking)
VI  - 47
IP  - 12
DP  - 2006 Dec
TI  - A prospective study of postictal psychoses with emphasis on the periictal type.
PG  - 2131-4
AB  - PURPOSE: To assess prospectively episodes of postictal psychosis. METHODS: We 
      followed 108 consecutive patients with temporal lobe epilepsy, who were divided 
      into three groups: those without psychotic episodes (n=87, N group), those with 
      interictal psychosis (n=13, IIP group), and those with postictal psychosis (n=8, 
      PIP group). The first episode of postictal psychosis, which was defined as a 
      psychotic episode that occurred within 1 week after the end or within 3 days 
      before the beginning of seizure clusters, was assessed with the Brief Psychiatric 
      Rating Scale (BPRS) and Social Dysfunction and Aggression Scale (SDAS) during the 
      observation period. RESULTS: The duration of illness was significantly different 
      between the N and PIP groups (p=0.004) and between the N and IIP groups 
      (p=0.039). The average initial BPRS score (obtained 3.0 days after the end of the 
      seizure cluster) was 19.7, and then decreased to 5.8 after 1 week, and finally 
      normalized at 1.5 after 1 month. A statistically significant decrease in BPRS 
      scores was found between the initial assessment and those obtained after 1 week 
      (p=0.011). Those who had psychotic episodes without a lucid interval tended to 
      have episodes more often than monthly, and experienced additional seizure 
      recurrence even during the psychotic episodes. Two patients exhibited a frank 
      manic phase, and three patients showed excessively aggressive behavior, as 
      determined by the SDAS. CONCLUSIONS: Postictal psychosis should be subdivided 
      into the nuclear type, with an established clinical picture as an indirect 
      aftereffect of seizure activity, and the atypical periictal type, which is a 
      direct manifestation of limbic discharge.
FAU - Oshima, Tomohiro
AU  - Oshima T
AD  - Department of Neuropsychiatry, Aichi Medical University, Aichi, Japan. 
      tomohirot@happytown.ne.jp
FAU - Tadokoro, Yukari
AU  - Tadokoro Y
FAU - Kanemoto, Kousuke
AU  - Kanemoto K
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Epilepsia
JT  - Epilepsia
JID - 2983306R
SB  - IM
MH  - Adult
MH  - Age of Onset
MH  - Aggression/psychology
MH  - Bipolar Disorder/diagnosis/epidemiology/psychology
MH  - Brief Psychiatric Rating Scale/*statistics & numerical data
MH  - Epilepsy, Complex Partial/diagnosis/physiopathology
MH  - Epilepsy, Temporal Lobe/*diagnosis/epidemiology/physiopathology
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Limbic System/physiopathology
MH  - Male
MH  - Prospective Studies
MH  - Psychiatric Status Rating Scales/statistics & numerical data
MH  - Psychometrics
MH  - Psychotic Disorders/*diagnosis/epidemiology/physiopathology
MH  - Recurrence
MH  - Social Adjustment
EDAT- 2007/01/05 09:00
MHDA- 2007/01/25 09:00
CRDT- 2007/01/05 09:00
PHST- 2007/01/05 09:00 [pubmed]
PHST- 2007/01/25 09:00 [medline]
PHST- 2007/01/05 09:00 [entrez]
AID - EPI806 [pii]
AID - 10.1111/j.1528-1167.2006.00806.x [doi]
PST - ppublish
SO  - Epilepsia. 2006 Dec;47(12):2131-4. doi: 10.1111/j.1528-1167.2006.00806.x.