PMID- 17209695
OWN - NLM
STAT- MEDLINE
DCOM- 20070315
LR  - 20181113
IS  - 0278-6133 (Print)
IS  - 0278-6133 (Linking)
VI  - 26
IP  - 1
DP  - 2007 Jan
TI  - A transdisciplinary model integrating genetic, physiological, and psychological 
      correlates of voluntary exercise.
PG  - 30-9
AB  - OBJECTIVE: Physical inactivity contributes to as many as 250,000 premature deaths 
      per year (R. R. Pate et al., 1995). The authors' objective was to test a 
      transdisciplinary model of the ways in which genetic variants, physiological 
      factors, and psychological factors are thought to influence exercise with 64 
      healthy, regular exercisers. DESIGN: In a within-subjects design, psychological 
      and physiological responses to exercise were compared with responses to a 
      sedentary activity. MAIN OUTCOME MEASURES: The authors measured affective state, 
      perceived exertion, heart rate, and temperature change in response to moderate 
      exercise versus sedentary activity. They also quantified genotypes on a single 
      nucleotide polymorphism in the brain-derived neurotrophic factor (BDNF) gene. 
      RESULTS AND CONCLUSIONS: The data show a relation between increases in positive 
      affective states and acute exercise behavior, as opposed to a sedentary control. 
      The BDNF gene moderated the effect of exercise on mood, heart rate, and perceived 
      exertion. Physiological factors were, in turn, related to mood response, and mood 
      response was a significant correlate of motivation to exercise in the future and 
      of current exercise behavior. The model has potential as a framework for the 
      basic study of the genetic, physiological, and psychological processes involved 
      with voluntary exercise and as a tool for the applied examination of tailored 
      exercise interventions and their efficacy for different subsets of individuals.
FAU - Bryan, Angela
AU  - Bryan A
AD  - University of Colorado at Boulder, Department of Psychology, Boulder, CO 
      80309-0345, USA. angela.bryan@colorado.edu
FAU - Hutchison, Kent E
AU  - Hutchison KE
FAU - Seals, Douglas R
AU  - Seals DR
FAU - Allen, David L
AU  - Allen DL
LA  - eng
GR  - R03 CA097870/CA/NCI NIH HHS/United States
GR  - R03 CA097870-02/CA/NCI NIH HHS/United States
GR  - R03 CA097870-01A1/CA/NCI NIH HHS/United States
GR  - M01 RR000051/RR/NCRR NIH HHS/United States
GR  - M01-RR00051/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - Health Psychol
JT  - Health psychology : official journal of the Division of Health Psychology, 
      American Psychological Association
JID - 8211523
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Affect/physiology
MH  - Body Temperature Regulation/genetics/physiology
MH  - Brain-Derived Neurotrophic Factor/*genetics
MH  - Exercise/*physiology/*psychology
MH  - Female
MH  - *Genotype
MH  - Heart Rate/genetics/physiology
MH  - Humans
MH  - Life Style
MH  - Male
MH  - Motivation
MH  - Physical Exertion/physiology
MH  - Polymorphism, Single Nucleotide/*genetics
MH  - Statistics as Topic
PMC - PMC1896050
MID - NIHMS21661
EDAT- 2007/01/11 09:00
MHDA- 2007/03/16 09:00
PMCR- 2007/06/22
CRDT- 2007/01/11 09:00
PHST- 2007/01/11 09:00 [pubmed]
PHST- 2007/03/16 09:00 [medline]
PHST- 2007/01/11 09:00 [entrez]
PHST- 2007/06/22 00:00 [pmc-release]
AID - 2006-23340-005 [pii]
AID - 10.1037/0278-6133.26.1.30 [doi]
PST - ppublish
SO  - Health Psychol. 2007 Jan;26(1):30-9. doi: 10.1037/0278-6133.26.1.30.