PMID- 1724191
OWN - NLM
STAT- MEDLINE
DCOM- 19920331
LR  - 20131121
IS  - 0173-0541 (Print)
IS  - 0173-0541 (Linking)
DP  - 1990
TI  - [Prevention of thrombosis with low molecular weight heparin and hydroxyethyl 
      starch in general surgery].
PG  - 1185-7
AB  - In an open, randomized, controlled and prospective study we compared the efficacy 
      of LMWH with unfractionated heparin (UFH) and the effects of both heparin 
      preparations on haemostatic and fibrinolytic parameters. We also stratified 
      subgroups which received HES intra- and postoperatively. The study groups were 
      well matched with regard to baseline characteristics. With LMWH 4 patients (4.1%) 
      displayed a positive fibrinogen uptake test (1 patient with HES). With UFH 5 
      patients (5%) demonstrated a positive uptake (3 patients with HES). Antifactor Xa 
      levels were significant higher in the LMWH groups; all other fibrinolytic and 
      haemostatic factors, bleeding and local wound complications did not differ. These 
      data suggest that LMWH in equally effective and safe as UFH in general surgery. 
      HES may have and additive effect.
FAU - Limmer, J
AU  - Limmer J
AD  - Allgemeinchirurgie, Universitat Ulm.
FAU - Seifried, E
AU  - Seifried E
FAU - Ellbruck, D
AU  - Ellbruck D
FAU - Schwarz, A
AU  - Schwarz A
LA  - ger
PT  - Clinical Trial
PT  - English Abstract
PT  - Journal Article
PT  - Randomized Controlled Trial
TT  - Thromboseprophylaxe mit niedermolekularem Heparin (LMWH) und Hydroxyaethylstarke 
      (HES) in der Allgemeinchirurgie.
PL  - Germany
TA  - Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir
JT  - Langenbecks Archiv fur Chirurgie. Supplement II, Verhandlungen der Deutschen 
      Gesellschaft fur Chirurgie. Deutsche Gesellschaft fur Chirurgie. Kongress
JID - 9200455
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 0 (Hydroxyethyl Starch Derivatives)
SB  - IM
MH  - Adult
MH  - Female
MH  - Heparin, Low-Molecular-Weight/*administration & dosage
MH  - Humans
MH  - Hydroxyethyl Starch Derivatives/*administration & dosage
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/*prevention & control
MH  - Prospective Studies
MH  - Thromboembolism/*prevention & control
EDAT- 1990/01/01 00:00
MHDA- 1990/01/01 00:01
CRDT- 1990/01/01 00:00
PHST- 1990/01/01 00:00 [pubmed]
PHST- 1990/01/01 00:01 [medline]
PHST- 1990/01/01 00:00 [entrez]
PST - ppublish
SO  - Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990:1185-7.