PMID- 17242783
OWN - NLM
STAT- MEDLINE
DCOM- 20070830
LR  - 20190917
IS  - 0104-4230 (Print)
IS  - 0104-4230 (Linking)
VI  - 52
IP  - 6
DP  - 2006 Nov-Dec
TI  - [Inadequacy of thromboprophylaxis in hospitalized medical patients].
PG  - 441-6
AB  - BACKGROUND: The risk of venous thromboembolism (VTE) is high in hospitalized 
      patients, however it can be reduced by adequate prophylaxis. OBJECTIVE: To 
      evaluate the adequacy of VTE prophylaxis in hospitalized medical patients. 
      METHODS: A cross-sectional study was performed in hospitalized patients with 
      acute medical illnesses in 4 hospitals of Salvador. RESULTS: We evaluated 226 
      consecutive patients: 15.5% in medical ICU, 79% > 40 years of age and 48% male. 
      The majority (97%) had a least 1 risk factor (RF) for VTE, 79% had reduced 
      mobility and 62% were diagnosed as having a RF at admission. Of the 208 
      prophylaxis candidates, 54% received some form of prophylaxis: unfractionated 
      heparin (UFH) in 44%, low molecular weight heparin (LMWH) in 56% and mechanical 
      methods in 2 patients. The utilization rate was similar in private and public 
      hospitals. (51% vs. 49%), but LMWH was more common in private hospitals, without 
      a residence program (97%), and UFH in the public ones (86%). LMWH was more 
      frequently used than UFH in patients > 40 years of age, more often in Caucasian 
      than in Black patients, and less frequently in those with contraindications for 
      heparin. Of the 112 patients receiving prophylaxis, 63% received adequate 
      dosages: LMWH in 95.2% and UFH in 20.4%. VTE prophylaxis was adequate in only 
      33.6% (70/208) of the patients. CONCLUSION: Risk Factors for VTE were frequent in 
      medical patients. There was considerable variability of the VTE prophylaxis 
      prescribed in private and public hospitals. LMWH was used more appropriately than 
      UFH. However, only a minority of patients candidates for prophylaxis, received 
      adequate dosages.
FAU - Rocha, Ana Thereza C
AU  - Rocha AT
AD  - Departamento de Medicina, Faculdade de Medicina da Bahia, Universidade Federal da 
      Bahia. anatrocha@alumni.duke.edu
FAU - Braga, Priscila
AU  - Braga P
FAU - Ritt, Guilherme
AU  - Ritt G
FAU - Lopes, Antonio Alberto
AU  - Lopes AA
LA  - por
PT  - English Abstract
PT  - Journal Article
TT  - Inadequacao de tromboprofilaxia venosa em pacientes clinicos hospitalizados.
PL  - Brazil
TA  - Rev Assoc Med Bras (1992)
JT  - Revista da Associacao Medica Brasileira (1992)
JID - 9308586
RN  - 0 (Anticoagulants)
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 9005-49-6 (Heparin)
SB  - IM
MH  - Adult
MH  - Anticoagulants/adverse effects/*therapeutic use
MH  - Cross-Sectional Studies
MH  - Female
MH  - Guidelines as Topic
MH  - Heparin/adverse effects/*therapeutic use
MH  - Heparin, Low-Molecular-Weight/adverse effects
MH  - *Hospitalization
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Regression Analysis
MH  - Risk Factors
MH  - Thromboembolism/*prevention & control
MH  - Venous Thrombosis/*prevention & control
EDAT- 2007/01/24 09:00
MHDA- 2007/08/31 09:00
CRDT- 2007/01/24 09:00
PHST- 2006/03/10 00:00 [received]
PHST- 2006/08/15 00:00 [accepted]
PHST- 2007/01/24 09:00 [pubmed]
PHST- 2007/08/31 09:00 [medline]
PHST- 2007/01/24 09:00 [entrez]
AID - S0104-42302006000600026 [pii]
AID - 10.1590/s0104-42302006000600026 [doi]
PST - ppublish
SO  - Rev Assoc Med Bras (1992). 2006 Nov-Dec;52(6):441-6. doi: 
      10.1590/s0104-42302006000600026.