PMID- 17255748
OWN - NLM
STAT- MEDLINE
DCOM- 20070507
LR  - 20220129
IS  - 0269-9370 (Print)
IS  - 0269-9370 (Linking)
VI  - 21
IP  - 3
DP  - 2007 Jan 30
TI  - Specificity of anti-human leukocyte antigen antibody responses after immunization 
      with Remune, an inactivated HIV-1 vaccine.
PG  - 375-7
AB  - Antibody responses against human leukocyte antigen (HLA) classes I and II were 
      detected in HIV-1 infected individuals who received a fixed inactivated HIV-1 
      (Remune) immunotherapy. The response was specific for HLA-B62 and HLA-DR4 
      concordant with the host cell line, HUT-78, used in vaccine production. These 
      responses were not detected in HLA-B62 and HLA-DR4-positive individuals 
      indicating that immunotherapy did not break tolerance to self-antigens.
FAU - Page, Mark
AU  - Page M
AD  - Division of Retrovirology, National Institute for Biological Standards and 
      Control, Potters Bar EN6 3QG, UK.
FAU - Ojugo, Agatha
AU  - Ojugo A
FAU - Imami, Nesrina
AU  - Imami N
FAU - Hardy, Gareth
AU  - Hardy G
FAU - Gotch, Frances
AU  - Gotch F
FAU - Almond, Neil
AU  - Almond N
LA  - eng
GR  - G0501957/MRC_/Medical Research Council/United Kingdom
GR  - G0600007/MRC_/Medical Research Council/United Kingdom
GR  - G0601201/MRC_/Medical Research Council/United Kingdom
GR  - G9025730/MRC_/Medical Research Council/United Kingdom
PT  - Clinical Trial, Phase I
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - AIDS
JT  - AIDS (London, England)
JID - 8710219
RN  - 0 (AIDS Vaccines)
RN  - 0 (HLA Antigens)
RN  - 0 (Isoantibodies)
RN  - 0 (Vaccines, Inactivated)
RN  - 0 (remune)
SB  - IM
MH  - AIDS Vaccines/*immunology
MH  - Antibody Specificity
MH  - Antiretroviral Therapy, Highly Active
MH  - *HIV-1
MH  - HLA Antigens/*immunology
MH  - Histocompatibility Testing
MH  - Humans
MH  - Isoantibodies/*biosynthesis
MH  - Male
MH  - Vaccines, Inactivated/immunology
EDAT- 2007/01/27 09:00
MHDA- 2007/05/08 09:00
CRDT- 2007/01/27 09:00
PHST- 2007/01/27 09:00 [pubmed]
PHST- 2007/05/08 09:00 [medline]
PHST- 2007/01/27 09:00 [entrez]
AID - 00002030-200701300-00015 [pii]
AID - 10.1097/QAD.0b013e328012b873 [doi]
PST - ppublish
SO  - AIDS. 2007 Jan 30;21(3):375-7. doi: 10.1097/QAD.0b013e328012b873.