PMID- 17260813
OWN - NLM
STAT- MEDLINE
DCOM- 20070306
LR  - 20131121
IS  - 0009-918X (Print)
IS  - 0009-918X (Linking)
VI  - 46
IP  - 9
DP  - 2006 Sep
TI  - [Case of herpes zoster associated Guillain-Barre syndrome with a relapse of 
      eruptions after intravenous immunoglobulin therapy].
PG  - 664-7
AB  - A 77-year-old woman developed progressive dysesthesia, hypesthesia and weakness 
      in four extremities immediately after improvement of herpes zoster in the left 
      Th10 dermatome area. Examination of the cerebrospinal fluid (CSF) showed an 
      increase in protein concentrations. Evidence of demyelinating polyneuropathy was 
      demonstrated by nerve conduction studies. Her hypesthesia and weakness in the 
      extremities were gradually improved following intravenous immunoglobulin therapy 
      (IVIg). Varicella zoster virus (VZV) titer levels in CSF well correlated both 
      with neurological symptoms and CSF protein concentrations. VZV DNA in the CSF was 
      not detectable. These findings suggested autoimmune Guillain-Barre syndrome (GBS) 
      associated with herpes zoster. An interesting finding in the present patient is 
      that one day after the completion of IVIg, when the neurological symptoms in the 
      extremities were apparently ameliorating, the herpes zoster eruptions again 
      emerged in the left L3 dermatome area. By treatment with intravenous acyclovir, 
      the vesicular eruptions were improved. We assume that IVIg might suppress the 
      immune response against VZV and promote the recurrence of eruptions.
FAU - Nagane, Yuriko
AU  - Nagane Y
AD  - Department of Neurology, Hanamaki General Hospital.
FAU - Utsugisawa, Kimiaki
AU  - Utsugisawa K
FAU - Obara, Daiji
AU  - Obara D
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Rinsho Shinkeigaku
JT  - Rinsho shinkeigaku = Clinical neurology
JID - 0417466
RN  - 0 (Antiviral Agents)
RN  - 0 (Immunoglobulins, Intravenous)
RN  - 0 (Immunologic Factors)
RN  - X4HES1O11F (Acyclovir)
SB  - IM
MH  - Acyclovir/therapeutic use
MH  - Aged
MH  - Antiviral Agents/therapeutic use
MH  - Female
MH  - Guillain-Barre Syndrome/*etiology
MH  - Herpes Zoster/drug therapy/*etiology
MH  - Herpesvirus 3, Human/immunology
MH  - Humans
MH  - Immunoglobulins, Intravenous/administration & dosage/*adverse effects
MH  - Immunologic Factors/administration & dosage/*adverse effects
MH  - Injections, Intravenous
MH  - Recurrence
EDAT- 2007/01/31 09:00
MHDA- 2007/03/07 09:00
CRDT- 2007/01/31 09:00
PHST- 2007/01/31 09:00 [pubmed]
PHST- 2007/03/07 09:00 [medline]
PHST- 2007/01/31 09:00 [entrez]
PST - ppublish
SO  - Rinsho Shinkeigaku. 2006 Sep;46(9):664-7.