PMID- 17262964
OWN - NLM
STAT- MEDLINE
DCOM- 20121022
LR  - 20070131
IS  - 0559-7765 (Print)
IS  - 0559-7765 (Linking)
VI  - 37
IP  - 4
DP  - 2006 Oct
TI  - [Immunoregulatory effect of dendritic cells and its signal transduction].
PG  - 313-8
AB  - Dendritic cells (DCs) are highly efficient antigen-presenting cells (APC). 
      Following antigen stimulating, DC could migrate from peripheral tissues to 
      lymphoid organs via chemotactic factors and up-regulate major histocompatibility 
      complex, costimulatory molecules, adhesion molecules, secreting cytokines, 
      acquiring the unique capacity to prime naive T cells. DC takes up antigen through 
      phagocytosis, pinocytosis, and endocytosis via different groups of receptor 
      families, such as C-type lectin receptors (CLRs) for antigen capture and 
      presentation, Toll-like receptors (TLRs) for pathogen recognition and DC 
      activation. The present review focuses on the progress of DC biology as well as 
      immunoregulation, activation via distinct pathogen recognition receptors and 
      intracellular signal transduction pathway.
FAU - Xu, Shan
AU  - Xu S
AD  - Burns Institute, First Hospital Affiliated to the PLA General Hospital, Beijing 
      100037, China.
FAU - Yao, Yong-Ming
AU  - Yao YM
FAU - Sheng, Zhi-Yong
AU  - Sheng ZY
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Review
PL  - China
TA  - Sheng Li Ke Xue Jin Zhan
JT  - Sheng li ke xue jin zhan [Progress in physiology]
JID - 20730140R
SB  - IM
MH  - Animals
MH  - Dendritic Cells/*immunology/*metabolism
MH  - Humans
MH  - Signal Transduction
EDAT- 2007/02/01 09:00
MHDA- 2012/10/23 06:00
CRDT- 2007/02/01 09:00
PHST- 2007/02/01 09:00 [pubmed]
PHST- 2012/10/23 06:00 [medline]
PHST- 2007/02/01 09:00 [entrez]
PST - ppublish
SO  - Sheng Li Ke Xue Jin Zhan. 2006 Oct;37(4):313-8.