PMID- 17265798 OWN - NLM STAT- MEDLINE DCOM- 20070308 LR - 20131121 IS - 0081-0746 (Print) IS - 0081-0746 (Linking) IP - 302 DP - 2006 TI - Sub-foveal choroidal blood flow by LDF: measurement and application to the physiology and pathology of the choroidal circulation. PG - 185-94 AB - Laser Doppler flowmetry allows the measurement of relative choroidal blood flow in the sub-foveal region of the fundus (ChBF). This technique has been applied to the investigation of the regulation of ChBF in response to a variety of physiological stimuli (breathing different gas mixtures of O2 and CO2, varying the systemic and ocular blood perfusion pressures, light-dark transition and zero gravity) in normal subjects. Measurements in pathological conditions, such as diabetes, age-related macular degeneration and glaucoma indicate alterations of the response of ChBF to increased systemic blood pressure. The data provide a better understanding of the regulation of the choroidal circulation in the normal and diseased eye. FAU - Riva, C E AU - Riva CE AD - Institut de Recherche en Ophtalmologie, Sion, Switzerland. charles.riva@netplus.ch LA - eng PT - Journal Article PT - Review PL - Belgium TA - Bull Soc Belge Ophtalmol JT - Bulletin de la Societe belge d'ophtalmologie JID - 7505353 RN - 0 (Myosin Subfragments) RN - 142M471B3J (Carbon Dioxide) RN - S88TT14065 (Oxygen) SB - IM MH - Administration, Inhalation MH - Animals MH - Carbon Dioxide/administration & dosage MH - Choroid/*blood supply MH - Diabetic Retinopathy/physiopathology MH - Fovea Centralis MH - Glaucoma/physiopathology MH - Humans MH - Intraocular Pressure/physiology MH - *Laser-Doppler Flowmetry MH - Light MH - Macular Degeneration/physiopathology MH - Myosin Subfragments MH - Oxygen/administration & dosage MH - Posture/physiology MH - Regional Blood Flow MH - Respiration MH - Weightlessness RF - 49 EDAT- 2007/02/03 09:00 MHDA- 2007/03/09 09:00 CRDT- 2007/02/03 09:00 PHST- 2007/02/03 09:00 [pubmed] PHST- 2007/03/09 09:00 [medline] PHST- 2007/02/03 09:00 [entrez] PST - ppublish SO - Bull Soc Belge Ophtalmol. 2006;(302):185-94.