PMID- 17266029
OWN - NLM
STAT- MEDLINE
DCOM- 20070417
LR  - 20160303
IS  - 0020-7136 (Print)
IS  - 0020-7136 (Linking)
VI  - 120
IP  - 9
DP  - 2007 May 1
TI  - Second primary malignancies in females with primary fallopian tube cancer.
PG  - 2047-51
AB  - Primary fallopian tube cancer (PFTC) is a rare disease, and its aetiological 
      factors are poorly understood. Studies on PFTC in the setting of 2nd primary 
      malignant neoplasms can provide clues on aetiology and also define the possible 
      side effects of different treatment modalities for PFTC. A cohort of 2,084 cases 
      with first PFTC was extracted from the data from 13 cancer registries from 
      Europe, Canada, Australia and Singapore and followed for second primary cancers 
      within the period 1943-2000. Standardized incidence ratios (SIRs) were calculated 
      and Poisson regression analyses were done to find out the RRs related to age at, 
      period of and time since the PFTC diagnosis. There were 118 cancer cases observed 
      after first PFTC (SIR 1.4, 95%CI 1.1-1.6). Elevated SIRs were seen for colorectal 
      cancer (1.7, 95%CI 1.0-2.6), for breast cancer (1.5, 95%CI 1.1-2.2), for bladder 
      cancer (2.8, 95%CI 1.0-6.0), for lung cancer (1.8, 95% CI 0.9-3.2) and for 
      nonlymphoid leukaemia (3.7, 95%CI 1.0-9.4). Significant risk increases were 
      detected for colorectal cancer during the 2nd to 5th year after the first PFTC 
      diagnosis, for breast cancer in follow-up 10+ and for nonlymphoid leukaemia 
      during the 2nd to 10th year. The clustering of cancers of the lung and bladder in 
      PFTC patients may suggest shared smoking aetiology. The excess of colorectal and 
      breast cancers after PFTC may indicate a genetic aetiology.
CI  - (c) 2007 Wiley-Liss, Inc.
FAU - Riska, Annika
AU  - Riska A
AD  - Department of Obstetrics and Gynecology, Helsinki University Central Hospital, 
      Finland.
FAU - Pukkala, Eero
AU  - Pukkala E
FAU - Scelo, Ghislaine
AU  - Scelo G
FAU - Mellemkjaer, Lene
AU  - Mellemkjaer L
FAU - Hemminki, Kari
AU  - Hemminki K
FAU - Weiderpass, Elisabete
AU  - Weiderpass E
FAU - McBride, Mary L
AU  - McBride ML
FAU - Pompe-Kirn, Vera
AU  - Pompe-Kirn V
FAU - Tracey, Elizabeth
AU  - Tracey E
FAU - Brewster, David H
AU  - Brewster DH
FAU - Kliewer, Erich V
AU  - Kliewer EV
FAU - Tonita, Jon M
AU  - Tonita JM
FAU - Kee-Seng, Chia
AU  - Kee-Seng C
FAU - Jonasson, Jon G
AU  - Jonasson JG
FAU - Martos, Carmen
AU  - Martos C
FAU - Boffetta, Paolo
AU  - Boffetta P
FAU - Brennan, Paul
AU  - Brennan P
LA  - eng
GR  - R03 CA101442-02/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Cancer
JT  - International journal of cancer
JID - 0042124
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Breast Neoplasms/epidemiology
MH  - Cohort Studies
MH  - Colorectal Neoplasms/epidemiology
MH  - Fallopian Tube Neoplasms/*complications/epidemiology
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Neoplasms, Second Primary/*epidemiology
MH  - Registries
EDAT- 2007/02/03 09:00
MHDA- 2007/04/18 09:00
CRDT- 2007/02/03 09:00
PHST- 2007/02/03 09:00 [pubmed]
PHST- 2007/04/18 09:00 [medline]
PHST- 2007/02/03 09:00 [entrez]
AID - 10.1002/ijc.22562 [doi]
PST - ppublish
SO  - Int J Cancer. 2007 May 1;120(9):2047-51. doi: 10.1002/ijc.22562.