PMID- 17270577
OWN - NLM
STAT- MEDLINE
DCOM- 20070518
LR  - 20151119
IS  - 0022-3999 (Print)
IS  - 0022-3999 (Linking)
VI  - 62
IP  - 2
DP  - 2007 Feb
TI  - Effectiveness of a meditation-based stress management program as an adjunct to 
      pharmacotherapy in patients with anxiety disorder.
PG  - 189-95
AB  - OBJECTIVE: The objective of this study was to examine the effectiveness of a 
      meditation-based stress management program in patients with anxiety disorder. 
      METHODS: Patients with anxiety disorder were randomly assigned to an 8-week 
      clinical trial of either a meditation-based stress management program or an 
      anxiety disorder education program. The Hamilton Anxiety Rating Scale (HAM-A), 
      the Hamilton Depression Rating Scale (HAM-D), the State-Trait Anxiety Inventory 
      (STAI), the Beck Depression Inventory, and the Symptom Checklist--90-Revised 
      (SCL-90-R) were used to measure outcome at 0, 2, 4, and 8 weeks of the program. 
      RESULTS: Compared to the education group, the meditation-based stress management 
      group showed significant improvement in scores on all anxiety scales (HAM-A, 
      P=.00; STAI state, P=.00; STAI trait, P=.00; anxiety subscale of SCL-90-R, P=.00) 
      and in the SCL-90-R hostility subscale (P=.01). Findings on depression measures 
      were inconsistent, with no significant improvement shown by subjects in the 
      meditation-based stress management group compared to those in the education 
      group. The meditation-based stress management group did not show significant 
      improvement in somatization, obsessive-compulsive symptoms, and interpersonal 
      sensitivity scores, or in the SCL-90-R phobic anxiety subscale compared to the 
      education group. CONCLUSIONS: A meditation-based stress management program can be 
      effective in relieving anxiety symptoms in patients with anxiety disorder. 
      However, well-designed, randomized, and controlled trials are needed to 
      scientifically prove the worth of this intervention prior to treatment.
FAU - Lee, Sang Hyuk
AU  - Lee SH
AD  - Department of Psychiatry, Pochon CHA University College of Medicine, Seongnam, 
      South Korea.
FAU - Ahn, Seung Chan
AU  - Ahn SC
FAU - Lee, Yu Jin
AU  - Lee YJ
FAU - Choi, Tae Kyu
AU  - Choi TK
FAU - Yook, Ki Hwan
AU  - Yook KH
FAU - Suh, Shin Young
AU  - Suh SY
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - England
TA  - J Psychosom Res
JT  - Journal of psychosomatic research
JID - 0376333
RN  - 0 (Anti-Anxiety Agents)
RN  - 41VRH5220H (Paroxetine)
RN  - O4L1XPO44W (Fluvoxamine)
RN  - QUC7NX6WMB (Sertraline)
RN  - YU55MQ3IZY (Alprazolam)
SB  - IM
MH  - Alprazolam/therapeutic use
MH  - Anti-Anxiety Agents/*therapeutic use
MH  - Anxiety Disorders/diagnosis/*drug therapy
MH  - Combined Modality Therapy
MH  - Fluvoxamine/therapeutic use
MH  - Humans
MH  - *Meditation
MH  - Paroxetine/therapeutic use
MH  - *Program Development
MH  - *Self Care
MH  - Sertraline/therapeutic use
MH  - Stress, Psychological/diagnosis/*prevention & control
MH  - Surveys and Questionnaires
EDAT- 2007/02/03 09:00
MHDA- 2007/05/19 09:00
CRDT- 2007/02/03 09:00
PHST- 2006/06/13 00:00 [received]
PHST- 2007/02/03 09:00 [pubmed]
PHST- 2007/05/19 09:00 [medline]
PHST- 2007/02/03 09:00 [entrez]
AID - S0022-3999(06)00431-4 [pii]
AID - 10.1016/j.jpsychores.2006.09.009 [doi]
PST - ppublish
SO  - J Psychosom Res. 2007 Feb;62(2):189-95. doi: 10.1016/j.jpsychores.2006.09.009.