PMID- 17276695
OWN - NLM
STAT- MEDLINE
DCOM- 20070629
LR  - 20081121
IS  - 1044-5323 (Print)
IS  - 1044-5323 (Linking)
VI  - 19
IP  - 1
DP  - 2007 Feb
TI  - Innate control of adaptive immunity: dendritic cells and beyond.
PG  - 48-55
AB  - Innate immune recognition of pathogens triggers both immediate defenses against 
      the invading pathogens and the initiation of adaptive immune responses. Dendritic 
      cells (DCs) play a key role in sensing and processing microbial information and 
      directing the differentiation of naive lymphocytes to effector cells suitable 
      against particular types of infections. These processes within DCs are 
      intricately controlled at the levels of the cell, anatomical location, migration 
      and their interaction with other cell types. This review focuses on recent 
      understanding of the contributions of several key cell types, which regulate, and 
      are regulated by DCs, in the generation of adaptive immune responses.
FAU - Lee, Heung Kyu
AU  - Lee HK
AD  - Section of Immunobiology, Yale University School of Medicine, New Haven, CT 
      06520, USA.
FAU - Iwasaki, Akiko
AU  - Iwasaki A
LA  - eng
GR  - AI054359/AI/NIAID NIH HHS/United States
GR  - AI062428/AI/NIAID NIH HHS/United States
GR  - AI064705/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20070205
PL  - England
TA  - Semin Immunol
JT  - Seminars in immunology
JID - 9009458
RN  - 0 (Toll-Like Receptors)
SB  - IM
MH  - Animals
MH  - Dendritic Cells/*immunology
MH  - Humans
MH  - *Immunity, Innate
MH  - Lymphocyte Activation
MH  - T-Lymphocytes, Regulatory/immunology
MH  - Toll-Like Receptors/*physiology
RF  - 100
EDAT- 2007/02/06 09:00
MHDA- 2007/06/30 09:00
CRDT- 2007/02/06 09:00
PHST- 2006/10/15 00:00 [received]
PHST- 2006/12/10 00:00 [accepted]
PHST- 2007/02/06 09:00 [pubmed]
PHST- 2007/06/30 09:00 [medline]
PHST- 2007/02/06 09:00 [entrez]
AID - S1044-5323(06)00121-7 [pii]
AID - 10.1016/j.smim.2006.12.001 [doi]
PST - ppublish
SO  - Semin Immunol. 2007 Feb;19(1):48-55. doi: 10.1016/j.smim.2006.12.001. Epub 2007 
      Feb 5.