PMID- 17288148
OWN - NLM
STAT- MEDLINE
DCOM- 20100603
LR  - 20161018
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 24
IP  - 6
DP  - 2006 Nov
TI  - [Determination of acrylamide in foods by gas chromatography-mass spectrometry].
PG  - 625-8
AB  - A confirmatory method is presented for the determination of acrylamide in 
      different food products by gas chromatography-mass spectrometry (GC-MS). The 
      method is based on the extraction of acrylamide with and methanol, and 
      purification with Carrez I zinc sulfate) and Carrez II (potassium 
      hexacyanoferrate) solution, followed by bromination onto the acrylamide double 
      bond. The derivative was extracted with ethyl acetate/hexane (4: 1, v/v), and 
      converted to the stable 2-bromopropenamide by dehydrobromination using 10% 
      triethylamine, then analyzed by GC-MS, employing 13C3-acrylamide as internal 
      standard. In-house validation data for flour and bread showed good accuracy and 
      precision of the method. The recoveries of acrylamide in the French fries and 
      bread were all in the range from 80% to 110% after correction of analyte loss by 
      the internal standard at three spike levels of 0.02, 0.05 and 0.2 mg/kg, and 
      relative standard deviations (RSDs) no more than 12.7%. The limits of detection 
      for flour and bread were estimated at 5 microg/kg.
FAU - Shen, Weijian
AU  - Shen W
AD  - Laboratory of food, Jiangsu Entry-Exit Inspection and Quarantine Bureau, Nanjing 
      21000, China. swj9722418@yahoo.com.cn
FAU - Shen, Chongyu
AU  - Shen C
FAU - Zhao, Zengyun
AU  - Zhao Z
FAU - Chen, Huilan
AU  - Chen H
FAU - Xu, Jinzhong
AU  - Xu J
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 20R035KLCI (Acrylamide)
SB  - IM
MH  - Acrylamide/*analysis
MH  - Bread/analysis
MH  - *Food Analysis
MH  - Gas Chromatography-Mass Spectrometry
MH  - Solanum tuberosum/chemistry
EDAT- 2007/02/10 09:00
MHDA- 2010/06/04 06:00
CRDT- 2007/02/10 09:00
PHST- 2007/02/10 09:00 [pubmed]
PHST- 2010/06/04 06:00 [medline]
PHST- 2007/02/10 09:00 [entrez]
PST - ppublish
SO  - Se Pu. 2006 Nov;24(6):625-8.