PMID- 17291344 OWN - NLM STAT- MEDLINE DCOM- 20070319 LR - 20230412 IS - 1471-2105 (Electronic) IS - 1471-2105 (Linking) VI - 8 DP - 2007 Feb 9 TI - PASSIM--an open source software system for managing information in biomedical studies. PG - 52 AB - BACKGROUND: One of the crucial aspects of day-to-day laboratory information management is collection, storage and retrieval of information about research subjects and biomedical samples. An efficient link between sample data and experiment results is absolutely imperative for a successful outcome of a biomedical study. Currently available software solutions are largely limited to large-scale, expensive commercial Laboratory Information Management Systems (LIMS). Acquiring such LIMS indeed can bring laboratory information management to a higher level, but often implies sufficient investment of time, effort and funds, which are not always available. There is a clear need for lightweight open source systems for patient and sample information management. RESULTS: We present a web-based tool for submission, management and retrieval of sample and research subject data. The system secures confidentiality by separating anonymized sample information from individuals' records. It is simple and generic, and can be customised for various biomedical studies. Information can be both entered and accessed using the same web interface. User groups and their privileges can be defined. The system is open-source and is supplied with an on-line tutorial and necessary documentation. It has proven to be successful in a large international collaborative project. CONCLUSION: The presented system closes the gap between the need and the availability of lightweight software solutions for managing information in biomedical studies involving human research subjects. FAU - Viksna, Juris AU - Viksna J AD - Institute of Mathematics and Computer Science, Riga, University of Latvia, Latvia. jviksna@mii.lu.lv FAU - Celms, Edgars AU - Celms E FAU - Opmanis, Martins AU - Opmanis M FAU - Podnieks, Karlis AU - Podnieks K FAU - Rucevskis, Peteris AU - Rucevskis P FAU - Zarins, Andris AU - Zarins A FAU - Barrett, Amy AU - Barrett A FAU - Neogi, Sudeshna Guha AU - Neogi SG FAU - Krestyaninova, Maria AU - Krestyaninova M FAU - McCarthy, Mark I AU - McCarthy MI FAU - Brazma, Alvis AU - Brazma A FAU - Sarkans, Ugis AU - Sarkans U LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20070209 PL - England TA - BMC Bioinformatics JT - BMC bioinformatics JID - 100965194 SB - IM MH - Artificial Intelligence MH - Biomedical Engineering/methods MH - Biomedical Research/methods MH - Clinical Trials as Topic/methods MH - *Database Management Systems MH - *Databases, Factual MH - Information Storage and Retrieval/*methods MH - *Medical Records Systems, Computerized MH - Programming Languages MH - *Software MH - *User-Computer Interface PMC - PMC1803798 EDAT- 2007/02/13 09:00 MHDA- 2007/03/21 09:00 PMCR- 2007/02/09 CRDT- 2007/02/13 09:00 PHST- 2006/07/25 00:00 [received] PHST- 2007/02/09 00:00 [accepted] PHST- 2007/02/13 09:00 [pubmed] PHST- 2007/03/21 09:00 [medline] PHST- 2007/02/13 09:00 [entrez] PHST- 2007/02/09 00:00 [pmc-release] AID - 1471-2105-8-52 [pii] AID - 10.1186/1471-2105-8-52 [doi] PST - epublish SO - BMC Bioinformatics. 2007 Feb 9;8:52. doi: 10.1186/1471-2105-8-52.