PMID- 17294156 OWN - NLM STAT- MEDLINE DCOM- 20070516 LR - 20181113 IS - 0941-293X (Print) IS - 0941-293X (Linking) VI - 104 IP - 3 DP - 2007 Mar TI - [The practicability of HLA matching]. PG - 219-21 AB - The unpredictability of the expected time on the waiting list has been the main barrier towards broad acceptance of human leukocyte antigen (HLA) matching in clinical routine. An algorithm for predicting the expected time on the waiting list for a histocompatible graft was recently introduced. This algorithm allows for the balancing waiting time against improvement in prognosis on an individual basis. HLAMatchmaker is a new method for identifying HLA mismatches with minor immunogenicity. This method is a valuable tool for providing patients who have a rare HLA phenotype with a histocompatible graft. In summary, new methods are now available that make histocompatibility in penetrating keratoplasty possible in almost all cases. FAU - Bohringer, D AU - Bohringer D AD - Universitatsaugenklinik Freiburg, Killianstrasse 5, 79106 Freiburg, Freiburg. daniel.boehringer@uniklinik-freiburg.de FAU - Reinhard, T AU - Reinhard T LA - ger PT - English Abstract PT - Journal Article PT - Review TT - Praktikabilitat des HLA-Matchings. PL - Germany TA - Ophthalmologe JT - Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft JID - 9206148 RN - 0 (ABO Blood-Group System) RN - 0 (Autoantigens) RN - 0 (HLA Antigens) SB - IM MH - ABO Blood-Group System/immunology MH - Autoantigens/*immunology MH - Corneal Diseases/*immunology/*surgery MH - Corneal Transplantation/*immunology/methods MH - Graft Rejection/immunology MH - Graft Survival/immunology MH - HLA Antigens/immunology MH - Histocompatibility Testing/*methods MH - Humans RF - 7 EDAT- 2007/02/13 09:00 MHDA- 2007/05/17 09:00 CRDT- 2007/02/13 09:00 PHST- 2007/02/13 09:00 [pubmed] PHST- 2007/05/17 09:00 [medline] PHST- 2007/02/13 09:00 [entrez] AID - 10.1007/s00347-006-1475-8 [doi] PST - ppublish SO - Ophthalmologe. 2007 Mar;104(3):219-21. doi: 10.1007/s00347-006-1475-8.