PMID- 17298107
OWN - NLM
STAT- MEDLINE
DCOM- 20070419
LR  - 20181201
IS  - 1175-0561 (Print)
IS  - 1175-0561 (Linking)
VI  - 8
IP  - 1
DP  - 2007
TI  - Coexistent psoriasis and lupus erythematosus treated with alefacept.
PG  - 47-50
AB  - Coexistence of psoriasis and subacute cutaneous lupus erythematosus (SCLE) is 
      unusual. Although there have been reports of this occurrence, there have been no 
      reports of this overlap syndrome treated with immunomodulators. We describe a 
      case of coexisting psoriasis and SCLE initially treated with infliximab, and then 
      alefacept. The patient's arthritis flared after the second infusion of 
      infliximab, which was discontinued. During treatment with alefacept, the 
      patient's psoriasis improved markedly without exacerbation of his photosensitive 
      SCLE lesions.
FAU - Berthelot, Cindy
AU  - Berthelot C
AD  - Department of Internal Medicine, University of Texas Houston Health Science 
      Center, Houston, TX, USA.
FAU - Nash, Jason
AU  - Nash J
FAU - Duvic, Madeleine
AU  - Duvic M
LA  - eng
GR  - K24-CA86815/CA/NCI NIH HHS/United States
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - New Zealand
TA  - Am J Clin Dermatol
JT  - American journal of clinical dermatology
JID - 100895290
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Dermatologic Agents)
RN  - 0 (Recombinant Fusion Proteins)
RN  - B72HH48FLU (Infliximab)
RN  - ELK3V90G6C (Alefacept)
SB  - IM
MH  - Adult
MH  - Alefacept
MH  - Antibodies, Monoclonal/adverse effects/therapeutic use
MH  - Dermatologic Agents/*therapeutic use
MH  - Humans
MH  - Infliximab
MH  - Lupus Erythematosus, Cutaneous/*complications/diagnosis/*drug therapy
MH  - Male
MH  - Psoriasis/*complications/diagnosis/*drug therapy
MH  - Recombinant Fusion Proteins/*therapeutic use
MH  - Skin/pathology
MH  - Treatment Outcome
EDAT- 2007/02/15 09:00
MHDA- 2007/04/20 09:00
CRDT- 2007/02/15 09:00
PHST- 2007/02/15 09:00 [pubmed]
PHST- 2007/04/20 09:00 [medline]
PHST- 2007/02/15 09:00 [entrez]
AID - 817 [pii]
AID - 10.2165/00128071-200708010-00007 [doi]
PST - ppublish
SO  - Am J Clin Dermatol. 2007;8(1):47-50. doi: 10.2165/00128071-200708010-00007.