PMID- 17299575
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20191110
IS  - 0016-9560 (Print)
IS  - 0016-9560 (Linking)
VI  - 40
IP  - 3
DP  - 2006 Sep
TI  - Seroprevalence of cytomegalovirus among some voluntary blood donors at the 37 
      military hospital, accra, ghana.
PG  - 99-104
AB  - SUMMARY BACKGROUND: Cytomegalovirus (CMV) is one of the most significant 
      pathogens infecting immunosuppressed individuals. CMV is transmissible through 
      transfusion of blood components. AIM: The goal of this study was to determine the 
      seroprevalence of antibodies to CMV among blood donors seen at the 37 Military 
      Hospital Blood Transfusion Unit, (MHBTU) Accra, Ghana. METHODS: The 
      seroprevalence of antibodies specific for CMV was tested using CMV IgG/IgM 
      particle agglutination test kit and ELISA. RESULTS: Of the 264 blood donors, 18 
      were negative and 246 were positive for CMV IgG antibodies, giving an overall CMV 
      prevalence rate of 93.2%. None of the 264 blood donors was positive for CMV IgM 
      antibodies. About 96% of the donors aged between 30 to 39 years were seropositive 
      for CMV, as against 91.9% in those aged 20-29 years, 88.6% in 40 to 49 years, 
      75.0% (3 out of 4) in 50 to 59 years, and 100% (1 out 1) in 60-69 years. There 
      was no statistically significant difference (P>0.05) in the CMV IgG status in 
      different age groups. The blood donors comprised largely of male donors (236 out 
      of 264), making sex comparisons statistically undesirable. However, all the 
      female (n=28) donors were positive for CMV IgG. CONCLUSION: Since about 93% of 
      blood donors at the MHBTU are seropositive for CMV, it would be very useful to 
      screen blood donors in Ghana for CMV to identify the very few CMV-seronegative 
      blood donors, and maintain an inventory of them for use as donors.
FAU - Adjei, Aa
AU  - Adjei A
AD  - Department of Pathology, University of Ghana Medical School, College of Health 
      Sciences, Korle-Bu, Accra, Ghana.
FAU - Armah, Hb
AU  - Armah H
FAU - Narter-Olaga, Eg
AU  - Narter-Olaga E
LA  - eng
PT  - Journal Article
PL  - Ghana
TA  - Ghana Med J
JT  - Ghana medical journal
JID - 0073210
PMC - PMC1790848
EDAT- 2007/02/15 09:00
MHDA- 2007/02/15 09:01
PMCR- 2006/09/01
CRDT- 2007/02/15 09:00
PHST- 2007/02/15 09:00 [pubmed]
PHST- 2007/02/15 09:01 [medline]
PHST- 2007/02/15 09:00 [entrez]
PHST- 2006/09/01 00:00 [pmc-release]
AID - jGMJ.v40.i3.pg99 [pii]
AID - 10.4314/gmj.v40i3.55261 [doi]
PST - ppublish
SO  - Ghana Med J. 2006 Sep;40(3):99-104. doi: 10.4314/gmj.v40i3.55261.