PMID- 17299806
OWN - NLM
STAT- MEDLINE
DCOM- 20080423
LR  - 20210416
IS  - 0885-6230 (Print)
IS  - 0885-6230 (Linking)
VI  - 22
IP  - 10
DP  - 2007 Oct
TI  - Reliability and validity of the Japanese version of the Dysexecutive 
      Questionnaire (DEX) in Alzheimer's disease: validation of a behavioral rating 
      scale to assess dysexecutive symptoms in Japanese patients with Alzheimer's 
      disease.
PG  - 951-6
AB  - BACKGROUND: Both executive cognitive dysfunction and behavioral problems 
      contribute to dysexecutive symptoms in daily life. The aim of the present study 
      was to develop a behavior rating scale for assessing dysexecutive symptoms in 
      Japanese patients with AD. METHOD: The Dysexecutive Questionnaire (DEX), devised 
      by Burgess et al. (1998), was used to evaluate 122 Japanese patients with AD. The 
      factor structure, internal consistency, test-retest reliability, and construct 
      validity of the Japanese version of the DEX were then examined. RESULTS: The 
      Japanese version of the DEX demonstrated a good internal reliability and a good 
      test-retest reliability. Factor analysis revealed three factors that were named 
      'apathy', 'hyperactivity' and 'planning and monitoring process of the purposive 
      action'. The 'apathy' factor of the DEX was significantly correlated with the 
      'apathy' score of the Neuropsychiatric Inventory (NPI), while 'planning and 
      monitoring process' factor of the DEX was significantly correlated with the total 
      score of the Frontal Assessment Battery (FAB) and the 'hyperactivity' factor of 
      the DEX was significantly correlated with the 'aggression', 'euphoria' and 
      'disinhibition' scores of the NPI. CONCLUSIONS: The Japanese DEX is a reliable 
      and valid instrument for assessing executive dysfunction conveniently in real 
      life situations of AD patients. While two factors, 'apathy' and 'hyperactivity', 
      were associated with emotional and behavioral changes, the 'planning and 
      monitoring process' was associated with the cognitive executive function in the 
      patients with AD. These findings suggest that both a neuropsychiatric syndrome 
      and cognitive function contribute to the dysexecutive symptoms experienced by AD 
      patients in daily life.
CI  - Copyright (c) 2007 John Wiley & Sons, Ltd.
FAU - Shinagawa, Yoshihiro
AU  - Shinagawa Y
AD  - Department of Psychiatry and Cognitive-behavioral Medicine, Nagoya City 
      University Graduate School of Medical Sciences, Mizuho-cho, Mizuho-ku, Nagoya 
      467-8601, Japan.
FAU - Nakaaki, Shutaro
AU  - Nakaaki S
FAU - Hongo, Jin
AU  - Hongo J
FAU - Murata, Yoshie
AU  - Murata Y
FAU - Sato, Junko
AU  - Sato J
FAU - Matsui, Teruo
AU  - Matsui T
FAU - Tatsumi, Hiroshi
AU  - Tatsumi H
FAU - Akechi, Tatsuo
AU  - Akechi T
FAU - Furukawa, Toshiaki A
AU  - Furukawa TA
LA  - eng
PT  - Journal Article
PT  - Validation Study
PL  - England
TA  - Int J Geriatr Psychiatry
JT  - International journal of geriatric psychiatry
JID - 8710629
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Alzheimer Disease/*psychology
MH  - Caregivers/*psychology
MH  - Female
MH  - Humans
MH  - Japan
MH  - Male
MH  - Psychiatric Status Rating Scales/*standards
MH  - Reproducibility of Results
MH  - Research Design/standards
MH  - Surveys and Questionnaires/*standards
EDAT- 2007/02/15 09:00
MHDA- 2008/04/24 09:00
CRDT- 2007/02/15 09:00
PHST- 2007/02/15 09:00 [pubmed]
PHST- 2008/04/24 09:00 [medline]
PHST- 2007/02/15 09:00 [entrez]
AID - 10.1002/gps.1768 [doi]
PST - ppublish
SO  - Int J Geriatr Psychiatry. 2007 Oct;22(10):951-6. doi: 10.1002/gps.1768.