PMID- 17300407
OWN - NLM
STAT- MEDLINE
DCOM- 20070322
LR  - 20191210
IS  - 0896-4327 (Print)
IS  - 0896-4327 (Linking)
VI  - 20
IP  - 1
DP  - 2007 Feb
TI  - Long-term results (up to 16.5 years) of mitral balloon valvuloplasty in a series 
      of 518 patients and predictors of long-term outcome.
PG  - 66-72
AB  - OBJECTIVES: To assess the long-term results (up to 16.5 years) of mitral balloon 
      valvuloplasty (MBV) and to identify predictors of restenosis and event-free 
      survival. METHODS AND RESULTS: We report the immediate and long-term clinical and 
      echocardiographic results in 518 patients, mean age 31 +/- 11 years, who 
      underwent successful MBV for severe mitral stenosis (MS) and were followed up for 
      0.5-16.5 (mean 6 +/- 4.5) years. After MBV, mitral valve area (MVA) increased 
      from 0.84 +/- 0.2 to 1.83 +/- 0.53 cm(2) (P < 0.0001) as measured by catheter and 
      from 0.92 +/- 0.17 to 1.96 +/- 0.29 cm(2) (P < 0.0001) as measured by 
      two-dimensional echo. Restenosis occurred in 111 patients (21%) and it was less 
      frequent in patients with low echo score (11%). Actuarial freedom from restenosis 
      at 5, 10, 15 years was 85 +/- 1%, 70 +/- 3%, and 44 +/- 5%, respectively, and was 
      significantly higher in patients with low echo score. Event-free survival (death, 
      redo MBV, mitral valve replacement, New York Heart Association [NYHA] functional 
      class III or IV) at 5, 10, 15 years was 89 +/- 1%, 79 +/- 2%, 43 +/- 9%, 
      respectively, and was significantly higher for patients with low echo score. Cox 
      regression analysis identified mitral echocardiographic score (MES) > 8 (P < 
      0.0001), postprocedure mitral valve area (MVA) (P = 0.0015), and preprocedure 
      functional class (P = 0.014) as predictors of restenosis and MES (P < 0.0001) and 
      age (P < 0.0001) and postprocedure MVA (P = 0.015) as predictors of event-free 
      survival. CONCLUSIONS: MBV provides excellent long-term results for selected 
      patients with MS. The long-term outcome after this procedure can be predicted 
      from baseline clinical and echocardiographic characteristics.
FAU - Fawzy, Mohamed E
AU  - Fawzy ME
AD  - King Faisal Heart Institute (MBC 16), King Faisal Specialist Hospital and 
      Research Center, Riyadh, Saudi Arabia. fawzy100@hotmail.com
FAU - Fadel, Bahaa
AU  - Fadel B
FAU - Al-Sergani, Hani
AU  - Al-Sergani H
FAU - Al Amri, Mohammed
AU  - Al Amri M
FAU - Hassan, Walid
AU  - Hassan W
FAU - Abdulbaki, Khalid
AU  - Abdulbaki K
FAU - Shoukri, Mohamed
AU  - Shoukri M
FAU - Canver, Charles
AU  - Canver C
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - United States
TA  - J Interv Cardiol
JT  - Journal of interventional cardiology
JID - 8907826
SB  - IM
MH  - Adult
MH  - *Catheterization
MH  - Disease-Free Survival
MH  - Echocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Mitral Valve Stenosis/diagnostic imaging/*mortality/physiopathology/*therapy
MH  - Postoperative Complications
MH  - Proportional Hazards Models
MH  - Recurrence
MH  - Saudi Arabia
MH  - Severity of Illness Index
MH  - Survival Analysis
MH  - Treatment Outcome
EDAT- 2007/02/16 09:00
MHDA- 2007/03/23 09:00
CRDT- 2007/02/16 09:00
PHST- 2007/02/16 09:00 [pubmed]
PHST- 2007/03/23 09:00 [medline]
PHST- 2007/02/16 09:00 [entrez]
AID - JOIC212 [pii]
AID - 10.1111/j.1540-8183.2007.00212.x [doi]
PST - ppublish
SO  - J Interv Cardiol. 2007 Feb;20(1):66-72. doi: 10.1111/j.1540-8183.2007.00212.x.