PMID- 17302220 OWN - NLM STAT- MEDLINE DCOM- 20070312 LR - 20081216 IS - 2072-0939 (Print) IS - 2072-0939 (Linking) VI - 29 IP - 6 DP - 2006 Nov-Dec TI - Survey of asthmatic patients' sensitization to house dust mites in southwestern Taiwan. PG - 568-75 AB - BACKGROUND: House dust mites (HDM) are one of the major risk factors for the development of bronchial asthma. The percentage of sensitization to HDM was reported to be 71.9% in Taipei City. In southwestern Taiwan, the percentage of sensitization to HDM has not been estimated. We retrospectively reviewed the medical records of asthmatic patients treated at the Chiayi branch of Chang Gung Memorial Hospital to investigate the percentage and associations with demographic characteristics. METHODS: We analyzed the data of 194 asthmatic patients diagnosed between January 2003 and July 2005. Sensitization to indoor allergens was identified by serum specific immunoglobulin E (IgE) of ImmunoCAP. Demographic characteristics of age, gender and residence were evaluated for associations with allergic sensitization. RESULTS: The percentage of sensitization to HDM was only 45.9% in patients in southwestern Taiwan. The majority of the studied group were elderly patients. The age variable significantly influenced the percentage of sensitization to HDM and cockroaches (p < 0.001 in both comparisons). The gender variable contributed to sensitization to cockroaches only (p = 0.002). For residential variables, there was no significant difference in the percentage of allergic sensitization to all tested indoor allergens among distinct areas of southwestern Taiwan. CONCLUSION: The percentage of sensitization to HDM in asthmatic patients residing in southwestern Taiwan was lower than that in metropolitan patients. This discrepancy might be attributed to the larger proportion of aged patients. FAU - Lin, Chin-Kuo AU - Lin CK AD - Department of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan, R.O.C. FAU - Hung, Ming-Szu AU - Hung MS FAU - Fang, Cheng-Pei AU - Fang CP FAU - Shen, Tzu-Yi AU - Shen TY FAU - Hsiao, Shih-Hsin AU - Hsiao SH FAU - Huang, Tung-Jung AU - Huang TJ FAU - Yang, Cheng-Ta AU - Yang CT LA - eng PT - Journal Article PL - China (Republic : 1949- ) TA - Chang Gung Med J JT - Chang Gung medical journal JID - 101088034 SB - IM MH - Adult MH - Age Factors MH - Aged MH - Animals MH - Asthma/*immunology MH - Female MH - Humans MH - Hypersensitivity/*epidemiology MH - Male MH - Middle Aged MH - Pyroglyphidae/*immunology MH - Retrospective Studies MH - Sex Factors MH - Taiwan/epidemiology EDAT- 2007/02/17 09:00 MHDA- 2007/03/14 09:00 CRDT- 2007/02/17 09:00 PHST- 2007/02/17 09:00 [pubmed] PHST- 2007/03/14 09:00 [medline] PHST- 2007/02/17 09:00 [entrez] AID - 2906/290605 [pii] PST - ppublish SO - Chang Gung Med J. 2006 Nov-Dec;29(6):568-75.