PMID- 17304326
OWN - NLM
STAT- MEDLINE
DCOM- 20080606
LR  - 20171116
IS  - 1671-167X (Print)
IS  - 1671-167X (Linking)
VI  - 39
IP  - 1
DP  - 2007 Feb 18
TI  - [Biomimetics of crystal texture in dental enamel prism by self-assembly 
      oligopeptide].
PG  - 46-9
AB  - OBJECTIVE: To evaluate the possibility of self-assembly oligopeptide(T2) for 
      dental enamel biomimetics, especially for the prism's crystal texture since it 
      could prompt calcium phosphate precipitated in gel carrier. METHODS: SEM 
      (Scanning electron microscope) and TEM (Transmission electron microscope) were 
      used to observe the morphologic presentation and ED(Electron diffraction) to 
      crystal texture comparing with the human molar enamel powder. RESULTS: (a) 
      Flake-like and needle-like octacalcium phosphate precipitated in the gel carrier 
      with self-assemble oligopeptide(T2). They transformed into rod-like 
      hydroxyapatite crystals gradually in the following 2-4 weeks. (b) The rod-like 
      hydroxyapatite may arrange or grow into bundles which are similar to the human 
      enamel prisms in both appearance and size. (c) The rod-like hydroxyapatite showed 
      polycrystal while the enamel prisms showed monocrystal under examination of ED. 
      CONCLUSION: The self-assemble oligopeptide(T2) could regulate the speed of 
      nucleation and crystallization of hydroxyapatite in morphology and crystalline 
      size. Thus, the self-assembly oligopeptide and the gel carrier mineralization 
      system could be primarily applied in biomimetic use for the crystallization of 
      hydroxyapatite in dental prism in vitro.
FAU - Wang, Lei
AU  - Wang L
AD  - Department of Prosthodontic, Peking University School & Hospital of Stomatology, 
      Beijing 100081, China.
FAU - Bai, Wei
AU  - Bai W
FAU - Feng, Hai-lan
AU  - Feng HL
FAU - Jia, Xin-ru
AU  - Jia XR
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Beijing Da Xue Xue Bao Yi Xue Ban
JT  - Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health 
      sciences
JID - 101125284
RN  - 0 (Calcium Phosphates)
RN  - 0 (Dental Enamel Proteins)
RN  - 0 (Oligopeptides)
RN  - 97Z1WI3NDX (calcium phosphate)
SB  - IM
MH  - Calcium Phosphates/*chemistry
MH  - Crystallization
MH  - Dental Enamel/*chemistry/metabolism/ultrastructure
MH  - Dental Enamel Proteins/*chemistry/ultrastructure
MH  - Humans
MH  - Microscopy, Electron, Transmission
MH  - Oligopeptides/*chemistry
EDAT- 2007/02/17 09:00
MHDA- 2008/06/07 09:00
CRDT- 2007/02/17 09:00
PHST- 2007/02/17 09:00 [pubmed]
PHST- 2008/06/07 09:00 [medline]
PHST- 2007/02/17 09:00 [entrez]
PST - ppublish
SO  - Beijing Da Xue Xue Bao Yi Xue Ban. 2007 Feb 18;39(1):46-9.