PMID- 17313544
OWN - NLM
STAT- MEDLINE
DCOM- 20070515
LR  - 20161124
IS  - 0742-2822 (Print)
IS  - 0742-2822 (Linking)
VI  - 24
IP  - 2
DP  - 2007 Feb
TI  - Evaluation of the relationship between functional capacity and right ventricular 
      diastolic function in patients with isolated mitral stenosis and sinus rhythm: a 
      tissue Doppler study.
PG  - 134-9
AB  - AIM: The right ventricular (RV) systolic function is an important determinant of 
      clinical symptoms and exercise capacity in patients with mitral stenosis. No 
      sufficient data are available concerning the effect of RV diastolic function on 
      symptoms of patients with mitral stenosis. In the presence of normal RV systolic 
      function, RV diastolic functions of asymptomatic patients with mitral stenosis of 
      moderate or severe degree were compared to symptomatic ones by pulsed-wave tissue 
      Doppler echocardiography in this study. MATERIALS AND METHODS: The study included 
      40 patients with mitral stenosis. Patients were classified into two groups 
      according to New York Heart Association (NYHA) class (asymptomatic group NYHA 
      class I, symptomatic group NYHA class II-III). RV diastolic functions were 
      evaluated via pulsed-wave tissue Doppler in terms of isovolumic contraction time 
      (IVCT), systolic wave velocity (S), isovolumic relaxation time (IVRT), early 
      diastolic wave velocity (E'), and late diastolic wave velocity (A'). RESULTS: 
      Statistical difference was not determined in systolic parameters (S, IVCT) 
      between the two groups. However, IVRT (54.21 +/- 11.93 msec vs 86.19 +/- 16.23 
      msec, P < 0.0001) and A' wave amplitude (10.16 +/- 2.14 cm/sec vs 13.55 +/- 3.35 
      cm/sec, P < 0.0001) were higher whereas E' wave amplitude (11.68 +/- 1.60 cm/sec 
      and 10.25 +/- 2.73 cm/sec, P = 0.009) and E'/A' ratio (1.18 +/- 0.23 vs 0.76 +/- 
      0.17, P < 0.0001) were lower in group 2. CONCLUSION: In isolated mitral stenosis, 
      pulsed-wave tissue Doppler may be used for the detection of RV diastolic 
      pathology. Diastolic functions of RV may deteriorate in the presence of normal 
      systolic functions in symptomatic patients with isolated mitral stenosis.
FAU - Saricam, Ersin
AU  - Saricam E
AD  - Turkiye Yuksek Ihtisas Education and Research Hospital, Department of Cardiology, 
      Ankara, Turkey.
FAU - Ozbakir, Cemal
AU  - Ozbakir C
FAU - Yildirim, Nesligul
AU  - Yildirim N
FAU - Tufekcioglu, Omac
AU  - Tufekcioglu O
FAU - Ocal, Arslan
AU  - Ocal A
FAU - Bascil, Selcuk
AU  - Bascil S
FAU - Bozboga, Seher
AU  - Bozboga S
FAU - Sabah Prof, Irfan
AU  - Sabah Prof I
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Echocardiography
JT  - Echocardiography (Mount Kisco, N.Y.)
JID - 8511187
SB  - IM
MH  - Adult
MH  - *Diastole
MH  - Echocardiography, Doppler, Color
MH  - *Echocardiography, Doppler, Pulsed
MH  - Electrocardiography
MH  - Exercise Tolerance/*physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Mitral Valve Stenosis/*diagnostic imaging/*physiopathology
MH  - Stroke Volume/*physiology
MH  - Ventricular Function, Right/*physiology
EDAT- 2007/02/23 09:00
MHDA- 2007/05/16 09:00
CRDT- 2007/02/23 09:00
PHST- 2007/02/23 09:00 [pubmed]
PHST- 2007/05/16 09:00 [medline]
PHST- 2007/02/23 09:00 [entrez]
AID - ECHO366 [pii]
AID - 10.1111/j.1540-8175.2007.00366.x [doi]
PST - ppublish
SO  - Echocardiography. 2007 Feb;24(2):134-9. doi: 10.1111/j.1540-8175.2007.00366.x.