PMID- 17318302
OWN - NLM
STAT- MEDLINE
DCOM- 20091123
LR  - 20181113
IS  - 1435-1463 (Electronic)
IS  - 0300-9564 (Linking)
VI  - 114
IP  - 7
DP  - 2007 Jul
TI  - Clinical and genetic features of families with frontotemporal dementia and 
      parkinsonism linked to chromosome 17 with a P301S tau mutation.
PG  - 947-50
AB  - In 9 patients with frontotemporal dementia and parkinsonism linked to chromosome 
      17 (FTDP-17) with a P301S tau mutation, the predominant phenotype was 
      frontotemporal dementia in 3 and parkinsonism in 6. Comparison of the tau 
      genotype/haplotype carrying the mutation and the initial clinical sign showed 
      association between H1/H1 and parkinsonism and between H1/H2 and personality 
      change. Thus, the tau haplotype carrying the mutation and the tau genotype may be 
      related to the clinical phenotype throughout the disease course.
FAU - Baba, Y
AU  - Baba Y
AD  - Department of Neurology, Mayo Clinic, Jacksonville, Florida 32224, USA.
FAU - Baker, M C
AU  - Baker MC
FAU - Le Ber, I
AU  - Le Ber I
FAU - Brice, A
AU  - Brice A
FAU - Maeck, L
AU  - Maeck L
FAU - Kohlhase, J
AU  - Kohlhase J
FAU - Yasuda, M
AU  - Yasuda M
FAU - Stoppe, G
AU  - Stoppe G
FAU - Bugiani, O
AU  - Bugiani O
FAU - Sperfeld, A D
AU  - Sperfeld AD
FAU - Tsuboi, Y
AU  - Tsuboi Y
FAU - Uitti, R J
AU  - Uitti RJ
FAU - Farrer, M J
AU  - Farrer MJ
FAU - Ghetti, B
AU  - Ghetti B
FAU - Hutton, M L
AU  - Hutton ML
FAU - Wszolek, Z K
AU  - Wszolek ZK
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20070223
PL  - Austria
TA  - J Neural Transm (Vienna)
JT  - Journal of neural transmission (Vienna, Austria : 1996)
JID - 9702341
RN  - 0 (tau Proteins)
SB  - IM
MH  - Adult
MH  - Chromosomes, Human, Pair 17/*genetics
MH  - Female
MH  - Frontotemporal Lobar Degeneration/*genetics/pathology
MH  - *Genetic Linkage
MH  - Genotype
MH  - Haplotypes/genetics
MH  - Humans
MH  - Male
MH  - Mutation/*genetics
MH  - Parkinsonian Disorders/*genetics/pathology
MH  - Young Adult
MH  - tau Proteins/*genetics
EDAT- 2007/02/24 09:00
MHDA- 2009/12/16 06:00
CRDT- 2007/02/24 09:00
PHST- 2007/01/15 00:00 [received]
PHST- 2007/01/16 00:00 [accepted]
PHST- 2007/02/24 09:00 [pubmed]
PHST- 2009/12/16 06:00 [medline]
PHST- 2007/02/24 09:00 [entrez]
AID - 10.1007/s00702-007-0632-9 [doi]
PST - ppublish
SO  - J Neural Transm (Vienna). 2007 Jul;114(7):947-50. doi: 10.1007/s00702-007-0632-9. 
      Epub 2007 Feb 23.