PMID- 17318511
OWN - NLM
STAT- MEDLINE
DCOM- 20070618
LR  - 20160512
IS  - 1618-2642 (Print)
IS  - 1618-2642 (Linking)
VI  - 388
IP  - 2
DP  - 2007 May
TI  - Determination of major and trace elements in human scalp hair by 
      pressurized-liquid extraction with acetic acid and inductively coupled 
      plasma-optical-emission spectrometry.
PG  - 441-9
AB  - An analytical method has been developed for determination of major (Ca, K, Mg, 
      and Na) and trace elements (As, Cd, Co, Li, Ni, and Sr) in human scalp hair. The 
      proposed method includes a novel, simple, rapid, highly efficient, and automated 
      metal-leaching procedure, by pressurized-liquid extraction (PLE), combined with a 
      rapid simultaneous detection system-inductively coupled plasma-optical-emission 
      spectrometry (ICP-OES). PLE is one of the most promising recently introduced 
      sample-preparation techniques, with the advantages of reducing solvent 
      consumption and enabling automated sample handling. The operating conditions for 
      PLE, including concentration of the extraction solvent, extraction temperature, 
      static time, number of extraction steps, pressure, mean particle size, 
      diatomaceous earth (DE) mass/sample mass ratio, and flush volume were studied 
      using an experimental design (Plackett-Burman design, PBD). The optimum 
      conditions were use of 0.75 mol L-1 acetic acid as extracting solution and 
      powdered hair samples thoroughly mixed with DE, as a dispersing agent, at a DE 
      mass/sample mass ratio of 4. Extraction was performed at room temperature and an 
      extraction pressure of 140 atm for 5 min in one extraction step. The flush volume 
      was fixed at 60%. The PLE-assisted multi-element leaching proposed is complete 
      after 7 min (5 min static time plus 1 min purge time plus 1 min end relief time). 
      Under the optimised conditions the figures of merit, for example limits of 
      detection and quantification, repeatability of the over-all procedure, and 
      accuracy, were evaluated. Analysis of GBW-07601 (human hair) certified reference 
      material revealed accuracy was good for the target elements. The optimised method 
      was finally applied to several human scalp-hair samples.
FAU - Moreda-Pineiro, Jorge
AU  - Moreda-Pineiro J
AD  - Department of Analytical Chemistry, Faculty of Sciences, University of A Coruna, 
      Campus da Zapateira s/n, 15071, A Coruna, Spain. jmoreda@udc.es
FAU - Alonso-Rodriguez, Elia
AU  - Alonso-Rodriguez E
FAU - Lopez-Mahia, Purificacion
AU  - Lopez-Mahia P
FAU - Muniategui-Lorenzo, Soledad
AU  - Muniategui-Lorenzo S
FAU - Prada-Rodriguez, Dario
AU  - Prada-Rodriguez D
FAU - Moreda-Pineiro, Antonio
AU  - Moreda-Pineiro A
FAU - Bermejo-Barrera, Pilar
AU  - Bermejo-Barrera P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20070223
PL  - Germany
TA  - Anal Bioanal Chem
JT  - Analytical and bioanalytical chemistry
JID - 101134327
RN  - 0 (Elements)
RN  - 0 (Trace Elements)
RN  - 61790-53-2 (Diatomaceous Earth)
RN  - Q40Q9N063P (Acetic Acid)
SB  - IM
MH  - Acetic Acid/*chemistry
MH  - Diatomaceous Earth
MH  - *Elements
MH  - Hair/*chemistry
MH  - Humans
MH  - Particle Size
MH  - Pressure
MH  - Reproducibility of Results
MH  - *Scalp
MH  - Spectrophotometry/*methods
MH  - Temperature
MH  - Trace Elements/*analysis/isolation & purification
EDAT- 2007/02/24 09:00
MHDA- 2007/06/19 09:00
CRDT- 2007/02/24 09:00
PHST- 2006/09/25 00:00 [received]
PHST- 2007/02/01 00:00 [accepted]
PHST- 2007/01/22 00:00 [revised]
PHST- 2007/02/24 09:00 [pubmed]
PHST- 2007/06/19 09:00 [medline]
PHST- 2007/02/24 09:00 [entrez]
AID - 10.1007/s00216-007-1179-1 [doi]
PST - ppublish
SO  - Anal Bioanal Chem. 2007 May;388(2):441-9. doi: 10.1007/s00216-007-1179-1. Epub 
      2007 Feb 23.