PMID- 17324050
OWN - NLM
STAT- MEDLINE
DCOM- 20070405
LR  - 20070227
IS  - 0735-7044 (Print)
IS  - 0735-7044 (Linking)
VI  - 121
IP  - 1
DP  - 2007 Feb
TI  - Time and stimulus specificity in extinction of the conditioned nictitating 
      membrane response in the rabbit (Oryctolagus cuniculus).
PG  - 50-62
AB  - The present experiments demonstrated that, in the rabbit nictitating membrane 
      preparation, a conditioned response (CR) can be selectively eliminated in one 
      portion of a conditioned stimulus (CS) while it is still paired with the 
      unconditioned stimulus (US). Rabbits were initially trained with two stimuli 
      (tone, light). Each was paired with the US by using a mixture of two CS-US 
      interstimulus intervals (ISIs): 200 ms and 1,200 ms in Experiment 1; 150 ms and 
      500 ms in Experiment 2. The CRs showed double peaks, one for each ISI. 
      Subsequently, one CS (A) was trained with only the longer ISI, whereas the other 
      CS (B) continued to be trained with both ISIs. Consequently, the CR peak based on 
      the shorter ISI disappeared for CSA but not for CSB. The later CR peaks during 
      both CSA and CSB were maintained. These results support time-based models of 
      conditioning. Implications for proposed mechanisms of extinction are discussed.
CI  - Copyright (c) 2007 APA, all rights reserved.
FAU - Joscelyne, A
AU  - Joscelyne A
AD  - School of Psychology, University of New South Wales, Sydney, NSW, Australia.
FAU - Kehoe, E James
AU  - Kehoe EJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Behav Neurosci
JT  - Behavioral neuroscience
JID - 8302411
SB  - IM
MH  - *Acoustic Stimulation
MH  - Adaptation, Physiological
MH  - Animals
MH  - Conditioning, Classical/*physiology
MH  - *Extinction, Psychological
MH  - Female
MH  - Nictitating Membrane/*physiology
MH  - Rabbits
MH  - Reaction Time/*physiology
MH  - Time Factors
EDAT- 2007/02/28 09:00
MHDA- 2007/04/06 09:00
CRDT- 2007/02/28 09:00
PHST- 2007/02/28 09:00 [pubmed]
PHST- 2007/04/06 09:00 [medline]
PHST- 2007/02/28 09:00 [entrez]
AID - 2007-02025-005 [pii]
AID - 10.1037/0735-7044.121.1.50 [doi]
PST - ppublish
SO  - Behav Neurosci. 2007 Feb;121(1):50-62. doi: 10.1037/0735-7044.121.1.50.