PMID- 17336073
OWN - NLM
STAT- MEDLINE
DCOM- 20070518
LR  - 20131121
IS  - 0968-0896 (Print)
IS  - 0968-0896 (Linking)
VI  - 15
IP  - 8
DP  - 2007 Apr 15
TI  - Free radical trapping properties of several ethyl-substituted derivatives of 
      5-ethoxycarbonyl-5-methyl-1-pyrroline N-oxide (EMPO).
PG  - 2827-36
AB  - The spin trapping behavior of several ethyl-substituted EMPO derivatives, cis- 
      and trans-5-ethoxycarbonyl-3-ethyl-5-methyl-pyrroline N-oxide (3,5-EEMPO), 
      5-ethoxycarbonyl-4-ethyl-5-methyl-pyrroline N-oxide (4,5-EEMPO), cis- and 
      trans-5-ethoxycarbonyl-5-ethyl-3-methyl-pyrroline N-oxide (5,3-EEMPO), and 
      5-ethoxycarbonyl-5-ethyl-4-methyl-pyrroline N-oxide (5,4-EEMPO), toward a series 
      of different oxygen- and carbon-centered radicals, is described. Considerably 
      different stabilities of the superoxide adducts (ranging from about 12 to 55 min) 
      as well as the formation of other radical adducts were observed.
FAU - Stolze, Klaus
AU  - Stolze K
AD  - Molecular Pharmacology and Toxicology Unit, Department of Natural Science, 
      University of Veterinary Medicine Vienna, Veterinarplatz 1, A-1210 Vienna, 
      Austria. Klaus.Stolze@vu-wien.ac.at
FAU - Rohr-Udilova, Natascha
AU  - Rohr-Udilova N
FAU - Rosenau, Thomas
AU  - Rosenau T
FAU - Hofinger, Andreas
AU  - Hofinger A
FAU - Nohl, Hans
AU  - Nohl H
LA  - eng
PT  - Journal Article
DEP - 20070215
PL  - England
TA  - Bioorg Med Chem
JT  - Bioorganic & medicinal chemistry
JID - 9413298
RN  - 0 (5-ethoxycarbonyl-5-methyl-1-pyrroline N-oxide)
RN  - 0 (Cyclic N-Oxides)
RN  - 0 (Free Radical Scavengers)
RN  - 0 (Indicators and Reagents)
RN  - 0 (Lipid Peroxides)
RN  - 11062-77-4 (Superoxides)
RN  - 3352-57-6 (Hydroxyl Radical)
RN  - E1UOL152H7 (Iron)
RN  - Y4S76JWI15 (Methanol)
SB  - IM
MH  - Catalysis
MH  - Cyclic N-Oxides/*chemical synthesis/*pharmacology
MH  - Electron Spin Resonance Spectroscopy
MH  - Free Radical Scavengers/*chemical synthesis/*pharmacology
MH  - Half-Life
MH  - Hydroxyl Radical/chemistry
MH  - Indicators and Reagents
MH  - Iron
MH  - Lipid Peroxides/chemistry
MH  - Magnetic Resonance Spectroscopy
MH  - Methanol/chemistry
MH  - Spectrometry, Mass, Electrospray Ionization
MH  - Spectrophotometry, Ultraviolet
MH  - Spectroscopy, Fourier Transform Infrared
MH  - Spin Trapping
MH  - Superoxides/chemistry
EDAT- 2007/03/06 09:00
MHDA- 2007/05/19 09:00
CRDT- 2007/03/06 09:00
PHST- 2006/12/06 00:00 [received]
PHST- 2007/02/06 00:00 [revised]
PHST- 2007/02/13 00:00 [accepted]
PHST- 2007/03/06 09:00 [pubmed]
PHST- 2007/05/19 09:00 [medline]
PHST- 2007/03/06 09:00 [entrez]
AID - S0968-0896(07)00128-9 [pii]
AID - 10.1016/j.bmc.2007.02.025 [doi]
PST - ppublish
SO  - Bioorg Med Chem. 2007 Apr 15;15(8):2827-36. doi: 10.1016/j.bmc.2007.02.025. Epub 
      2007 Feb 15.