PMID- 17351082 OWN - NLM STAT- MEDLINE DCOM- 20070629 LR - 20220427 IS - 1545-9683 (Print) IS - 1545-9683 (Linking) VI - 21 IP - 3 DP - 2007 May-Jun TI - Establishing the minimal clinically important difference of the Barthel Index in stroke patients. PG - 233-8 AB - BACKGROUND: The interpretation of the change scores of the Barthel Index (BI) in follow-up or outcome studies has been hampered by the fact that its minimal clinically important difference (MCID) has not been determined. OBJECTIVE: This article was written to establish the MCID of the BI in stroke patients. METHODS: Both anchor-based and distribution-based methods were used to establish the MCID. In the anchor-based method, 43 stroke inpatients participated in a follow-up study designed to determine the MCID of the BI using patients' global ratings of the activities of daily living function on a 15-point Likert-type scale. The mean change scores on the 20-point scale of the BI of the MCID group, based on the patients' ratings on the Likert-type scale, served as the first estimate of the MCID. In the distribution-based method, 56 chronic stroke patients participated in the test-retest reliability study to determine the MCID of the BI. One standard error of measurement (SEM) served as the second estimate for the MCID. The larger MCID value of the 2 estimates was chosen as the MCID of the BI. RESULTS: In the anchor-based study, there were 20 patients in the MCID group, with a mean change score of 1.85 points (ie, the first MCID estimate). In the distribution-based study, the SEM based on test-retest agreement was 1.45 points (ie, the second MCID estimate). The MCID of the BI in stroke patients was estimated to be 1.85 points. CONCLUSION: The authors' results, within the limitations of their design, suggest that if the mean BI change score within a stroke group has reached 1.85 points in a study, the change score on the BI can be perceived by patients as important and beyond measurement error (ie, such a change score is clinically important). FAU - Hsieh, Yu-Wei AU - Hsieh YW AD - School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan. FAU - Wang, Chun-Hou AU - Wang CH FAU - Wu, Shwu-Chong AU - Wu SC FAU - Chen, Pau-Chung AU - Chen PC FAU - Sheu, Ching-Fan AU - Sheu CF FAU - Hsieh, Ching-Lin AU - Hsieh CL LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Validation Study DEP - 20070309 PL - United States TA - Neurorehabil Neural Repair JT - Neurorehabilitation and neural repair JID - 100892086 SB - IM MH - *Activities of Daily Living MH - Adult MH - Aged MH - Data Interpretation, Statistical MH - *Disability Evaluation MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Psychomotor Performance MH - Reproducibility of Results MH - Severity of Illness Index MH - Stroke/*physiopathology MH - *Stroke Rehabilitation EDAT- 2007/03/14 09:00 MHDA- 2007/06/30 09:00 CRDT- 2007/03/14 09:00 PHST- 2007/03/14 09:00 [pubmed] PHST- 2007/06/30 09:00 [medline] PHST- 2007/03/14 09:00 [entrez] AID - 1545968306294729 [pii] AID - 10.1177/1545968306294729 [doi] PST - ppublish SO - Neurorehabil Neural Repair. 2007 May-Jun;21(3):233-8. doi: 10.1177/1545968306294729. Epub 2007 Mar 9.