PMID- 17353181 OWN - NLM STAT- MEDLINE DCOM- 20081104 LR - 20151119 IS - 1080-2924 (Print) IS - 1080-2924 (Linking) VI - 13 IP - 1 DP - 2007 TI - Blastoid mantle cell lymphoma occurring in a patient in complete remission of chronic myelogenous leukemia. PG - 30-3 AB - The development of a de novo lymphoma in patients affected by chronic myelogenous leukemia (CML) is a rare event. The introduction of new molecular cytogenetic techniques, such as fluorescence in situ hybridization (FISH), allows a correct differential diagnosis between lymphoid blastic crisis and a blastoid variant of mantle cell lymphoma (MCL), which shows an aggressive behavior and some molecular characteristics detectable by cytogenetics and immunohistochemistry. We report a case of a blastoid variant of MCL that developed in a patient with CML who achieved complete cytogenetic and molecular response to imatinib mesylate treatment. FAU - Garzia, M AU - Garzia M AD - Dipartimento di Diagnostica Morfologica, Microbiologica, Molecolare e delle Malattie del Sangue, Catholic University of Sacred Heart, Rome, Italy. FAU - Sora, F AU - Sora F FAU - Teofili, L AU - Teofili L FAU - Di Mario, A AU - Di Mario A FAU - Voso, M T AU - Voso MT FAU - Rumi, C AU - Rumi C FAU - La Rocca, L M AU - La Rocca LM FAU - Sica, S AU - Sica S FAU - Zini, G AU - Zini G LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Lab Hematol JT - Laboratory hematology : official publication of the International Society for Laboratory Hematology JID - 9615688 RN - 0 (Antineoplastic Agents) RN - 0 (Benzamides) RN - 0 (Piperazines) RN - 0 (Pyrimidines) RN - 8A1O1M485B (Imatinib Mesylate) SB - IM MH - Antineoplastic Agents/therapeutic use MH - Benzamides MH - Fatal Outcome MH - Humans MH - Imatinib Mesylate MH - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*complications/drug therapy MH - Lymphoma, Mantle-Cell/*complications/*pathology MH - Male MH - Middle Aged MH - Piperazines/therapeutic use MH - Pyrimidines/therapeutic use MH - Remission Induction EDAT- 2007/03/14 09:00 MHDA- 2008/11/05 09:00 CRDT- 2007/03/14 09:00 PHST- 2007/03/14 09:00 [pubmed] PHST- 2008/11/05 09:00 [medline] PHST- 2007/03/14 09:00 [entrez] AID - 4W564520053X4083 [pii] AID - 10.1532/LH96.06030 [doi] PST - ppublish SO - Lab Hematol. 2007;13(1):30-3. doi: 10.1532/LH96.06030.