PMID- 17355423
OWN - NLM
STAT- MEDLINE
DCOM- 20070515
LR  - 20151119
IS  - 0959-4493 (Print)
IS  - 0959-4493 (Linking)
VI  - 18
IP  - 2
DP  - 2007 Apr
TI  - Pilot study: prevalence of positive aeroallergen reactions in 10 cats with 
      small-airway disease without concurrent skin disease.
PG  - 94-100
AB  - The purpose of this study was to determine the prevalence of positive allergen 
      reactions in cats with small-airway disease (i.e. 'feline asthma', 'feline 
      allergic bronchitis', 'feline bronchial disease'). Intradermal skin tests (IDT) 
      and serum immunoglobulin E (IgE) tests were performed in 10 cats with idiopathic 
      small-airway disease and in 10 normal cats without a history of respiratory 
      disease. None of the cats had a history of skin disease or clinical signs of skin 
      disease at the time of testing. Significantly more individual positive allergen 
      reactions were found on serum IgE tests than on IDT in both groups of cats. 
      Affected cats had significantly more individual positive allergen reactions on 
      both tests than unaffected cats. Both IDT and serum IgE tests resulted in more 
      individual positive allergen reactions to weeds, trees, grasses, and/or moulds in 
      affected cats than in normal cats. Significantly more positive allergen reactions 
      to house dust mites were found in affected compared to non-affected cats by IDT 
      but not by serum IgE testing. One unexpected obstacle to inclusion of more 
      affected cats in the study was the concurrent presence or history of suspect or 
      known allergic skin disease. Concurrent allergic skin disease has not been 
      reported in association with small-airway disease in cats. The increased 
      prevalence of individual positive allergen reactions in affected cats may be due 
      to increased immunological reactivity in these cats. Further studies are needed 
      to answer this question and to determine what role, if any, aeroallergens have in 
      the pathogenesis of this complex feline disease.
FAU - Moriello, Karen A
AU  - Moriello KA
AD  - Department of Medical Sciences, School of Veterinary Medicine, University of 
      Wisconsin-Madison, 2015 Linden Drive West, Madison, WI 53706, USA. 
      moriellk@svm.vetmed.wisc.edu
FAU - Stepien, Rebecca L
AU  - Stepien RL
FAU - Henik, Rosemary A
AU  - Henik RA
FAU - Wenholz, Lisa J
AU  - Wenholz LJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Vet Dermatol
JT  - Veterinary dermatology
JID - 9426187
RN  - 0 (Allergens)
RN  - 0 (Immunoglobulin G)
SB  - IM
MH  - Allergens
MH  - Animals
MH  - Asthma/complications/epidemiology/*veterinary
MH  - Case-Control Studies
MH  - Cat Diseases/*epidemiology
MH  - Cats
MH  - Dermatitis/complications/epidemiology/*veterinary
MH  - Female
MH  - Immunoglobulin G/blood
MH  - Intradermal Tests/veterinary
MH  - Male
MH  - Prevalence
MH  - Prospective Studies
MH  - Wisconsin/epidemiology
EDAT- 2007/03/16 09:00
MHDA- 2007/05/16 09:00
CRDT- 2007/03/16 09:00
PHST- 2007/03/16 09:00 [pubmed]
PHST- 2007/05/16 09:00 [medline]
PHST- 2007/03/16 09:00 [entrez]
AID - VDE573 [pii]
AID - 10.1111/j.1365-3164.2007.00573.x [doi]
PST - ppublish
SO  - Vet Dermatol. 2007 Apr;18(2):94-100. doi: 10.1111/j.1365-3164.2007.00573.x.